FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
JUNE 2016
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
SURGICAL ONCOLOGY
PAPER I
SURG.ONCO/J/16/47/I
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. What is gene signature and define its role in cancer management?
Types and role of gene signatures in the management of breast
cancer.
5+5
2. Good Clinical Practice guidelines.
Rationale and planning of phase-III clinical trial.
5+5
3. What is Biobanking? Mention its advantages.
Components of Biobanking.
6+4
4. Enumerate the process and components of informed consent.
What are WHO surgical safety guidelines?
5+5
5. Patient selection criteria for metastasectomy.
Role of metastasectomy in colo-rectal cancer management.
5+5
6. Principles and rationale behind screening for cancer.
Current status of screening for breast, cervical and lung cancer.

7. What is a Cancer Registry and discuss various types of Cancer
Registries?
Global epidemiological trends of lung and breast cancer.

8. Define surgical palliation with clinical examples.
Quality of life assessment tools.
5+5
9. Define Precision Medicine with rationale and advantages.
Tyrosine kinase pathway.
Indications, dose and duration of imatinib in GIST patients.

10. Role of human papilloma virus in head and neck cancers.
Cervical cancer vaccine.
5+5