FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
JUNE 2018

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
SURGICAL ONCOLOGY
PAPER-I
SURGONCO/J/18/47/I
Time: 3 hours
Max. Marks:100
Important Instructions:
Attempt all questions in order.
Each question carries 10 marks.
Read the question carefully and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space
Answer all the parts of a single question together.
Start the answer to a question on a fresh page or leave adequate space between two answers.
Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. What are the specimen requirements for molecular diagnostics and
cytogenetics? What is the importance of cytogenetics testing in
diagnosis of soft tissue sarcoma?
4+6
2. Enumerate cancers attributable to tobacco smoking according to
level of evidence available. Add a note on carcinogenic substances
present in tobacco products and their role in carcinogenesis.

3. Discuss the basis for fractionation in radiation therapy and its types
with examples and current applications.

4. What is targeted therapy? What is the role of targeted therapy in the
management of non-metastatic solid organ malignancies with
examples?
2+8
5. Discuss various criteria and tools available for assessing the clinical
response. Add a note on predictive Serum Biomarkers.
7+3
6. What is Meta-analysis? How does it differ from systematic review?
Discuss results of any one meta-analysis each in Head and neck
and Breast Cancer.

7. Discuss the principle and various approaches to Mandibular
preservation with respect to indications, contraindications,
advantages and disadvantages.
10
8. What are the rehabilitation concerns in a patient undergoing total
maxillectomy? How will you address each one of them?
4+6
9. Mutational landscape of colorectal cancer and its therapeutic
implications.
5+5
10. Discuss the changes in 8th edition of AJCC/TNM staging of cancers
and discuss the staging of oral, lung, colorectal and gallbladder
cancer.