FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
SURGICAL ONCOLOGY
PAPER I
Time 3 hours SURG.ONCO/D/17/47/I
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two
answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. What is gene sequencing?
Its usefulness in diagnosis and treatment of cancer
4+6
2. Draw cell cycle
Effects of Radiotherapy in various phases of cell cycle
Name check points and their significance

3. Viral etiology for cancer. Discuss on pathogenesis of cancer
due to virus in
HIV Cancer
Cancer Cervix virus
4
3
3
4. Basic surgical principles in cancer surgery
Impact of HIPEC in management of Psuedomyxoma
peritonei.
6+4
5. Design of phase III clinical trial and analysis of the results of
clinical trials.
6+4
6. Mention IHC markers of breast cancer.
prognosis based on molecular subtypes
5+5
7. Enumerate types of delivery of radiation in cancer.
Advantages of IORT and proton beam therapy.
4+6
8. Mechanism of PARP inhibitors
Mention PARP Inhibitors
Future prospects

9. Management of head and neck squamous cell carcinoma-
Metastases to regional lymph nodes.
Types of Neck Dissections for lymph nodal metastases.
5+5
10. Discuss on Tumour micro environment during cancer invasion
and metastases.
5+5