FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
JUNE 2017
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
SURGICAL ONCOLOGY
PAPER I
SURGONCO/J/17/47/I
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. What are the factors contributing to cancer associated thrombosis?
Prophylaxis and management of thrombosis in a surgical patient.

2. What is "sequencing"?
What is Next Generation Sequencing?
Impact of Next Generation Sequencing in oncology.

3. Meta-analysis.
Impact factor.
6+4
4. What is standard fractionation?
What are the altered fractionation techniques available?
Advantages and disadvantages of hyperfractionation.

5. What is Minimally Invasive Surgery
Impact of MIS on outcomes in oncology.
3+7
6. Treatment of neuropathic pain.
Long acting opioids.
5+5
7. Name the different phases of cell cycle.
Explain role of cyclin dependent kinases.
Regulation of cell cycle.

8. Advantages of a cohort study.
Median survival.
6+4
9. What is prophylactic surgery in oncology?
Indications, techniques and current status of contra-lateral
prophylactic mastectomy.
6+4
10. Classify platinum compounds.
Their mechanisms of action, indications and their toxicity.
3+7