Exam Details
| Subject | dosage form design –i | |
| Paper | ||
| Exam / Course | b.pharm | |
| Department | ||
| Organization | Gujarat Technological University | |
| Position | ||
| Exam Date | November, 2017 | |
| City, State | gujarat, ahmedabad |
Question Paper
Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Pharm SEMESTER-VII • EXAMINATION WINTER-2017
Subject Code: 2270001 Date: 02-11-2017
Subject Name: Dosage Form Design-I
Time: 10:30 am to 01:30 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Explain the influence of chemical properties of drugs on formulation and stability of the products.
06
Discuss theoretical aspects for determining solubility and permeability of
the drug and its assessment.
05
Enlist additives used in tablet dosages form. Discuss the anti frictional agents.
05
Q.2
Write a note on prodrugs.
06
Effect of physical properties of drug like physical form, particle size and shape on formulation, stability and bioavailability.
05
Write a note on Biodegradable polymers.
05
Q.3
Explain the role of biopharmaceutics in formulation development.
06
Write a note on polymers used for achieving modified drug release.
05
Explain various types of equivalence. How Latin square cross over design works?
05
Q.4
Write a note on factors affecting drug absorption.
06
Discuss the regulatory requirements for conduction of bio-equivalence
studies.
05
Volunteer selection for bioavailability studies is a critical issue. Discuss the
statement with examples.
05
Q.5
Enumerate the drug transport mechanisms. Discuss passive diffusion in detail.
06
What is BCS classification? How does it affect development of dosage form?
05
How temperature degradation study is applied to pharmaceutical formulations?
Derive an equation for half-life and method to establish expiry date and
overages in formulations.
05
Q. 6
Write in detail about facilitated diffusion and pinocytosis.
06
Explain USP dissolution apparatus III, IV and V with diagram.
05
Discuss the factors affecting stability of pharmaceutical formulation.
05
Q.7
What is the importance of protein binding of drugs? Describe tissue binding of
drugs in detail.
06
Storage conditions for stability testing as per ICH guidelines.
05
What is matrixing and bracketing?
05
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Pharm SEMESTER-VII • EXAMINATION WINTER-2017
Subject Code: 2270001 Date: 02-11-2017
Subject Name: Dosage Form Design-I
Time: 10:30 am to 01:30 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Explain the influence of chemical properties of drugs on formulation and stability of the products.
06
Discuss theoretical aspects for determining solubility and permeability of
the drug and its assessment.
05
Enlist additives used in tablet dosages form. Discuss the anti frictional agents.
05
Q.2
Write a note on prodrugs.
06
Effect of physical properties of drug like physical form, particle size and shape on formulation, stability and bioavailability.
05
Write a note on Biodegradable polymers.
05
Q.3
Explain the role of biopharmaceutics in formulation development.
06
Write a note on polymers used for achieving modified drug release.
05
Explain various types of equivalence. How Latin square cross over design works?
05
Q.4
Write a note on factors affecting drug absorption.
06
Discuss the regulatory requirements for conduction of bio-equivalence
studies.
05
Volunteer selection for bioavailability studies is a critical issue. Discuss the
statement with examples.
05
Q.5
Enumerate the drug transport mechanisms. Discuss passive diffusion in detail.
06
What is BCS classification? How does it affect development of dosage form?
05
How temperature degradation study is applied to pharmaceutical formulations?
Derive an equation for half-life and method to establish expiry date and
overages in formulations.
05
Q. 6
Write in detail about facilitated diffusion and pinocytosis.
06
Explain USP dissolution apparatus III, IV and V with diagram.
05
Discuss the factors affecting stability of pharmaceutical formulation.
05
Q.7
What is the importance of protein binding of drugs? Describe tissue binding of
drugs in detail.
06
Storage conditions for stability testing as per ICH guidelines.
05
What is matrixing and bracketing?
05
Other Question Papers
Subjects
- agronomy and forestry of medicinal plants
- anatomy physiology & health education -ii
- anatomy, physiology and health education (aphe)
- applied mathematics (biostatistics)
- basic computer applications
- basic concepts of pharmacology and clinical pharmacy practice
- basics of computer applications
- bioavailability & therapeutic drug monitoring
- bioavailability and therapeutic drug monitoring
- biochemistry
- clinical pharmacy ii
- clinical pharmacy-i
- commerce of herbs and phytoconstitutents
- computer applications in drug discovery
- current advances in novel drug delivery systems
- cyber security
- disaster management
- dispensing pharmacy i
- dispensing pharmacy i and drug store management
- dispensing pharmacy ii and pharma industrial management
- dosage form design –i
- dosage form design- i
- dosage form design- ii
- dosage form design-i
- dosage form design-ii
- drug approval process
- environmental studies
- environmental toxicology and green audit
- food analysis
- forensic pharmacy
- forensic pharmacy-i
- genetic engineering and gene therapy
- green chemistry
- health education and community health
- herbal cosmetics
- hospital and community pharmacy
- hospital management and medical tourism
- hospital pharmacy, community pharmacy & forensic pharmacy
- hospital pharmacy, community pharmacy and dispensing pharmacy-ii
- human anatomy physiology
- human anatomy physiology and health education-ii
- human anatomy physiology-ii
- human anatomy, physiology and health education - i
- innovations in conventional drug delivery system
- instrumental and process validation
- intellectual property rights and patents
- medical writing and coding
- medicinal biochemistry
- nutraceuticals
- pathophysiology
- pharmaceutical analysis ii
- pharmaceutical analysis iii
- pharmaceutical analysis iv
- pharmaceutical analysis-i
- pharmaceutical analysis-ii
- pharmaceutical analysis-iv
- pharmaceutical chemistry – ii
- pharmaceutical chemistry – vi (organic chemistry – ii)
- pharmaceutical chemistry –viii (medicinal chemistry - ii)
- pharmaceutical chemistry iii
- pharmaceutical chemistry iv
- pharmaceutical chemistry vii
- pharmaceutical chemistry-i
- pharmaceutical chemistry-i (inorganic chemistry)
- pharmaceutical chemistry-ii (physical chemistry)
- pharmaceutical chemistry-iii (biochemistry – i)
- pharmaceutical chemistry-iv (organic chemistry-i)
- pharmaceutical chemistry-ix (medicinal chemistry-iii)
- pharmaceutical chemistry-v
- pharmaceutical chemistry-v (biochemistry-ii)
- pharmaceutical chemistry-vi (medicinal)
- pharmaceutical chemistry-vii
- pharmaceutical chemistry-viii
- pharmaceutical chemistry-x
- pharmaceutical chemistry-x (medicinal chemistry-iii)
- pharmaceutical engineering
- pharmaceutical engineering-ii
- pharmaceutical inorganic chemistry
- pharmaceutical marketing management
- pharmaceutical microbiology - i
- pharmaceutical microbiology & biotechnology i
- pharmaceutical microbiology &biotechnology- ii
- pharmaceutical microbiology and biotechnology - ii
- pharmaceutical organic chemistry
- pharmaceutical technology - i
- pharmaceutical technology – i
- pharmaceutical technology- ii
- pharmaceutical technology-i
- pharmaceutical technology-ii
- pharmaceutics-i
- pharmaceutics-ii
- pharmaceutivcal chemistry ix
- pharmacognosy iii
- pharmacognosy iv
- pharmacognosy vi
- pharmacognosy vii
- pharmacognosy vii (herbal formulations & complimentary therapies)
- pharmacognosy-i
- pharmacognosy-ii
- pharmacognosy-iii
- pharmacognosy-iv
- pharmacognosy-v
- pharmacognosy-v (plant bio technology)
- pharmacognosy-vi
- pharmacology -iii
- pharmacology & pharmacotherapeutics-ii
- pharmacology and pharmacotherapeutics - i
- pharmacology and pharmacotherapeutics - iii
- pharmacology and pharmacotherapeutics-iv
- pharmacology-i
- pharmacology-ii
- pharmacovigilance
- pharmacy practice
- physical pharmaceutics-ii
- physical pharmacy
- quality by design (qbd) and process analytical technology (pat)
- regulatory aspects of food and neutraceuticals
- remedial mathematics
- unit operation - i
- unit operation - ii