FACULTY OF PHARMACY
B. Pharmacy 3/4 I-Semester (Suppl.) Examination, April 2018
Subject Pharmacology I
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 What are different routes of drug administration? Explain the merits and demerits
of oral and parental routes of administration.
Define the following:
Therapeutic Index
Biological Half life
Tachyphylaxis
OR
Define and classify the receptors. Explain in detail about ion channel linked
receptors.
Write about different types of Phase-I reactions.
2 Explain the pharmacological effects and therapeutic uses of
Prazosin
Atropine
Proponolol
OR
Classify the cholinergic agents with examples. Write their actions on
Heart, Bronchioles, Intestine and Eye.
Add a note on their therapeutic uses.
3 Write about the classification of anti-depressant agents. Write in detail about the
mechanism of action, therapeutic uses and adverse reactions of tricyclic
antidepressants.
OR
Classify anti-epileptic agents and explain the mechanism of action and
therapeutic uses of any three classes of drugs.
4 Define Hyperlipedemia. Classify the anti-hyperlipedemic agents. Discuss the
mechanism of action and therapeutic uses of any two drugs of different classes.

OR
What is bronchial asthma? Classify anti-asthmatic drugs. Explain the
pharmacology of any two drugs.
5 Define Diuresis. Classify Diuretics and explain mechanism of action, adverse
reactions and therapeutic uses of furosemide and spironolactone.
OR
Write short notes on the pharmacology of:
H2 receptor blockers
Anti diarrhoeals