FACULTY OF PHARMACY
B. Pharmacy 3/4 I-Semester (Suppl.) Examination, May 2017
Subject Pharmacology I
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 What are different routes of drug administration? Compare the merits and demerits
of oral and parenteral routes of administration.
Define the following:
Therapeutic Index
Biological Half life
Synergism
OR
Define and classify the receptors. Explain in detail about G-protein coupled
receptors.
Write short notes on LD50 and ED50.
2 Explain the pharmacological effects and therapeutic uses of
Physostigmine
Atropine
Propronolol
(iv)Hyoscine
OR
Classify the adrenergic agents with examples. Write their actions on
Heart, Bronchioles, Intestine and Eye.
Add a note on their therapeutic uses.
3 Write about the classification of anti-depressant agents. Write in detail about the
mechanism of action, therapeutic uses and adverse reactions of SSRIs.
OR
Define Parkinsonism. Classify anti-Parkinson's drugs with examples? Write the
mechanism of action and therapeutic uses of COMT inhibitors and MAO
inhibitors.
4 Define arrhythmias. Classify the anti-arrhythmic agents. Discuss the pharmacology
of any two drugs of different classes.
OR
What is bronchial asthma? Classify anti-asthmatic drugs. Explain the pharmacology
of any two drugs.
5 Define Diuresis. Classify Diuretics and explain mechanism of action, adverse
reactions and therapeutic uses of carbonic anhydrase inhibitors and potassium
sparing diuretics.
OR
Write about the pharmacology of Purgatives.
Write the mechanism of action and therapeutic uses of following drugs:
Ondansetron
Pantoprazole