FACULTY OF PHARMACY
B. Pharmacy 3/4 I Semester (Main) Examination, November 2017
Subject Pharmacology I
Time 3 hours Max. Marks 70
Note Answer all questions. All questions carry equal marks.
1 Write about various phase I biotransformation reactions with examples. 8
Define the following
Synergism ii) Biological Half life iii) Tolerance 6
OR
Explain in detail about the advantages and disadvantages of different routes
of drug administration. 14
2 Classify cholinergic agents and explain the pharmacological effects of acetyl
choline. 4+5
Explain the various therapeutic uses and adverse reactions of Atropine. 5
OR
Explain the mechanism of action and therapeutic uses of the following 14
Adrenaline ii) Propronolol iii) Physostigmine
iv) Hyoscine
3 Classify anti-epileptic agents and explain the mechanism of action, adverse
reactions and therapeutic uses of any three classes of drugs. 5+9
OR
Write the classification of Non-steroidal anti-inflammatory agents and explain
the details of any three classes of drugs. 5+9
4 Define hypertension. Classify the antihypertensive agents with examples.
Write about the mechanism of action and adverse reactions of angiotensin
receptor blockers and calcium channel blockers.
OR
Write short notes on 7+7
Bronchodilators
ii) Drugs used in the treatment of shock
5 Classify the agents used in treatment of peptic ulcer disease. Write about the
pharmacological actions and therapeutic uses of Omeprazole and Rantidine. 4+6
Write short notes on carbonic anhydrase inhibitors. 4
OR
Write about the following 7+7
Anti-diarrhoeal agents
ii) Anti-emetic agents