FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016

POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PATHOLOGY
PAPER I
PATH/D/16/32/I
Time 3 hours
Max. Marks 100
IMPORTANT INSTRUCTIONS
• This question paper consists of 10 questions divided into Part and Part each part
containing 5 questions.
• Answers to questions of Part and Part are to be strictly attempted in separate answer
sheet(s) and the main supplementary answer sheet(s) used for each part must be tagged
separately.
• Answers to questions of Part attempted in answer sheet(s) of Part or vice versa shall
not be evaluated.
• Answer sheet(s) of Part and Part are not to be tagged together.
• Part and Part should be mentioned only on the covering page of the respective answer
sheet(s).
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
PART A
1. What are Xenobiotics? Write the pathways of Xenobiotic
metabolism.
Define bioterrorism. Categorise various potential agents of
bioterrorism.

2. Role of endothelium in hemostasis.
Pathogenesis of thrombosis.
Fate of thrombus.

3. Tensins in carcinogenesis
DNA repair defects and cancer.
5+5
4. Principle of Fluorescent in Situ Hybridisation (FISH).
Enumerate its applications.
Mention various karyotypes found in Turner's syndrome, and
methods for prenatal diagnosis of Turner's syndrome.
3+3
2+2
5. Pathogenesis, classification and diagnosis of amyloidosis.

P.T.O.