FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
PATHOLOGY
PAPER I

POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
Time 3 hours PATH/D/17/32/I
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two
answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Acquired predisposing conditions in neoplasia.
Pathophysiology of septicemic shock
5+5
2. Histopathological findings in lepra reactions
Automated semen analysis
5+5
3. Protein accumulations with examples.
Cell adhesion molecules.
5+5
4. Mechanisms of apoptosis
Role of microbial agents in pathogenesis of
atherosclerosis.
5+5
5. Morphology of renal changes in systemic lupus
erythematosus.
Necroptosis.
5+5
6. Technique and applications of tissue microarray
Pathogenesis and pathology of osteoporosis
5+5
7. Mechanisms of tumour evasion of immune
surveillance.
Mechanism and sequelae of ATP depletion in cell
injury.
5+5
8. Mechanisms that counteract cellular aging.
Defects in innate immunity.
5+5
9. Pathogenesis and pathology of syphilis.
Trouble shooting in immunohistochemistry
5+5
10. Diagnostic utility of direct immunofluorescence in
cutaneous bullous disorders.
Mechanism of immunodeficiency in HIV
5+5