FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
JUNE 2016
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PATHOLOGY
PAPER I
PATH/J/16/32/I
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Molecular pathology of embryonal tumours of the CNS.
Pathogenesis of anaphylactic shock.
5+5
2. Haematopoietic stem cells: regulatory network and
De novo generation.
DNA mismatch repair defects in carcinogenesis.
5+5
3. In-vitro diagnosis of hypersensitivity reaction.
Pathogenesis of ageing.
5+5
4. Thromboembolism in children.
Principle applications of confocal microscope.
5+5
5. GATA 3 and its role in tumour diagnosis.
Hypocomplementemia and its disorders.
5+5
6. Major abnormalities in immune functions in patients of
AIDS.
Chemotaxis and chemotactic agents.
5+5
7. Autophages.
Chromosomal instability.
5+5
8. Hyper IgM syndrome.
Monoclonality of a tumour.
5+5
9. Preneoplastic disorders.
Structure of amyloid.
5+5
10. Disorders of endogenous pigments.
APUD cells of GIT.
5+5