1. Which statements are correct about orthoboric acid

Its basic character is less in polyhydroxy organic compounds than in water

It can be titrated against NaOH in presence of glycerol using phenophthaline

It is a very weak tri-basic acid

It ionizes water to form and H2B03-

2. Homolytic fission of C-C bond in ethane gives an intermediate in which carbon is

Sp3 hybridized .

Sp2 hybridized

Sp hybridized

Sp3d hybridized

3. Benzyl cation is stabilized by

resonance

hyper-conjugation

H2 bonding

Inductive

4. In which of the following minerals Al is not present

Diaspore

Cryolite

Feispar

Flouspar

5. H2O2 cannot act as

Oxidizing agent

Reducing agent

Antichlor

Dehydrating agent

6. Pair of elements with equal values of electro negativity

Be, Al

Mg, Al

Mg, Ca

F,Ne

7. The ratio of energies of radiations having wavelengths of 800nm and 400nm is

1:2

2:1

4:1

1:4


8. Which of the following samples has the largest mass

1.42cm3 diamond density -2.84grmcm3)

0.75 cm3 opal density-2.20 grmcm3)

1.00 cm3 ivory density-1.9grmcm3)

0.65 cm3 coal density-2.7grmcm3)

9. The organic portion of bone consist of which of the following proteins

fibrin

collagen

actin

myosin

10. A culture of bacteria produces 5 generations in 2 hours. What is the generation time for this bacterium under those conditions

12 minutes

15 minutes

24 minutes

30 minutes

11. The Nobel Prize in physiology and medicine for the year 2013 recognized the contributions in the field of

Innate and adaptive immunity

Vesicle trafficking in the cells

RNA interference

Neuroscience


12. Beer's law states that

Absorbance is proportional to both the path length and concentration ofthe absorbing species

Absorbance is proportional to the log of the concentration of the absorbing species

Absorbance is equal to P0/P

None of the above

13. The following is not a class of pro-biotic organisms

Bifidobacterium

Lactobacillus

Saccharomyces

Streptococcus

14. Benzoylation of phenol in alkaline medium is known as

Friedel Craft reaction

Wurtz-Fitting reaction

reaction

Sahatier-Sander reaction


15. Two tubes ofnuc1eic acids marked X and Y were analyzed for their base composition:
Tube-X was found to have 33 percent 17 percent 17 percent and 33 percent T and
Tube-Y was 37 percent 16 percent 22 percent and 25 percent T. Which of the following statements are correct with respect to the nature ofthe nucleic acids in the two tubes

Tube X has double stranded RNA while Tube Y has single stranded DNA

Tube X has double stranded DNA while Tube Y has single stranded RNA

Tube X has double stranded DNA while Tube Y has single stranded DNA

Tube X has single stranded DNA while Tube Y has double stranded DNA

16. You engineered a bacteriophage that had the protein coat of T2 phage and the DNA of 14 phage. The composite bacteriophage was allowed to infect bacteria. What would be the composition of the new phages produced in the bacterial cells

New phages would have the protein coat of T2 and the DNA of T4

New phages would have the protein coat and DNA of T2

New phages would have the protein coat and DNA of T4

New phages would have a mixture of the DNA and proteins of both phages

17. The following compounds have identical molecular weights. Which would have the lowest boiling point

1-Butanol

2-Methyl-l-propanol

1,1-Dimethylethanol

1-Methoxypropane

18. A concentrated solution of k2CrO4 is 15% by weight and the density is 1.129 g/cm3. How many grams of the solution are required to prepare 200.00 ml of a 0.150% solution (Atomic weight; K 39.10, Cr 52.0,0 16.00)

41.4

34.2

40.5

38.8

19. Structure that have the same evolutionary origin even though they may now have different structure or function are said to be

endemic

analogous

homologous

geometric

20. An object is placed at 10 cm in front of a concave mirror of radius of curvature 15 cm. The nature and magnification of the image in each case will be

Real and inverted

Virtual and erect

Real and erect

Virtual and inverted


21. The angular displacement of a particle is given by Q=5t4+100t3+t2/2+8t/3+200. Its angular velocity after 0.3s is

20 rads-l

30.51 rads-1

54.3 rads-l

33.22 rads-1

22. The angle between the vectors and is equal to (in degrees)

0

45

60

90

23. A die is thrown three times. What is the probability of getting 5 on the third throw

1/6

1/18

1/36

1/216

24. The median for the following data set is

Observed values 20 25 30 35 40 45
Frequency 4 5 3 4 7 5

30

32.5

35

37.5

25. Choose the correct match

GROUPl GROUP2
P. IgA 1. Basophils
Q. IgE 2. gama heavy chain
R. IgG 3. Secretory component
S. IgM 4. Pentamer
5. Crosses placenta

S-4

S-1

8-4

Q-l 8-5



26. One of the following is the most common and chronic multifactorial disease

Diabetes

Typhoid

HIV infection

Malaria

27. Which will have enantiomers

n-butyl chloride

ter-butyl chloride

sec-butyl chloride

pri-butyl chloride

28. One of the following is not a DNA sequencing method

Maxam-Gilbert sequencing

Sanger Sequencing

Pyrosequencing

MALDI-TOF

29. The following is not an essential part oftranslational machinery

Ribosomal subunits

Messenger RNA

tRNA

Endoplasmic reticulum

30. One of the following is not an antibiotic

Tetracycline

Rifabutin

Amoxycillin

Betamethasone

31. Which of the following processes shuffle DNA of an organism

Transposition

Mutation

Pseudogenization

All of the above

32. Identify the correct order of electron transport seen during oxygenic photosynthesis

QB to QA to PC

Pheophytin to QA to QB

QA to QB to p680

p700 to p680 to PQ pool



33. Which one of the following is a single celled bacterium

Nostoc

Synechocystis

Anaebena

Synechococcus

34. The bioinformatic database, DDBJ is maintained by

Japan

Europe

India

USA

35. The signal sensor of a two component signal transduction systems

Histidine kinase

Serine kinase

Response regulator

Repressor

36. The bond between a fatty acid and glycerol moiety in a phospholipid is

Phosphodiester bond

Ester bond

Ionic bond

Glycosidic linkage

37. Which among the following organisms are oldest

Fungi

Diplomonads

Archaea

Dicots

38. In Gram staining, the primary stain which is useful for identification of bacferia is

Crystal violet

Safranin

Methyl red

Methyl orange

39. The common character for both living and non-living organisms is

Cells

Movement

Molecules

HOlneostasis



40. Mad cow disease is caused by

Prions

Protozoa

Fungus

Unknown

41. The enzyme reverse transcriptase is for

Killing the virus

Avoiding the virus infection

Making cDNA from RNA

Making RNA from DNA

42. The term that is used for the bacteria which can withstand pasteurization but does not grow at higher temperatures

Thermoduric

Thermophiles

Extreme thermophiles

Facultative thermophiles

43. Ribose sugar is present in

RNA only

RNAandATP

RNA polymerase and ATP

RNA polymerase, RNA and ATP

44. The type of gamates produced by an individual with genotype Aa Bb are

AB; ab

ab; AB

aB; Ab

All of the above

45. Mycoplasma differ frolll the other prokaryotes in the

Absence of cell wall

Presence of proteins in cell wall

Presence of chitin in cell wall

Presence of cellulose in cell wall

46. If glucose labeled with 14C in position 1 is added to a bacterial culture under anaerobic conditions, which carbon atom of lactic acid would be labeled

The methyl carbon

The carboxyl carbon

The chiral carbon

All three carbons


47. The most abundant organic molecule on earth

Flavonoids

Lipids

Lignin

Hemicellulose

48. Which of the following technique is used for quantification of mRNA

Real-time PCR

Western Blotting

Gradient PCR

Nested PCR

49. Which is the best chromatographic method to separate a protein that binds strongly to its substrate

Gel filtration

Affinity

Ion exchange

Hydrophobic interaction

50. In the medium other than nutrients, if any substance is used in excess, that mediunl is

Simple medium

Enriched medium

Special medium

Enrichment medium

51. The ratio 1 is the expected ratio in an F2 progeny of a single gene (monohybrid cross)

Phenotypes when one of the alleles is dominant

Genotypes when one allele is dominant

Combinations of heterozygous genotypes

Combinations of Homozygous genotypes

52. Which of the following point mutations would be most likely to affect protein function

CAA to CTA

CAA to TAA

GAA to CAA

TAA to TGA


53. Following molecules are associated with copper and magnesium, respectively

Plastocyanin and DNA polymerase

Plastoquinone and chlorophyll

Cytochrome and DNA polymerase

PSI reaction centre protein and chlorophyll


54. Rapid but non-antigen specific immune responses are produced by the

Adaptive immune response

Innate immune system

Leukocytes

Lymphatic system

55. The term aero tolerant anaerobe refers to an organism that

prefers to grow without oxygen

requires less oxygen than is present in air

doesn't use oxygen but can grow in the presence oxygen

uses oxygen when present or grows without oxygen when absent

56. Industrial microbiologists use "tricks" to increase the amount of chosen end product; this may include
Manipulating the growth environment

Selecting microbial strains that lack a feedback system

Both

None


57. Cells that release histamine and other vasoactive substances in response to allergens are

neutrophils

macrophages

NK cells

mast cells

58. Which of the following disease is not an autoimmune disease

rheumatoid arthritis

lupus erythematosis

bovine spongiform encephalitis

grave's disease

59. Which of the following are true with regard to interferons

Activates B cells to make virus specific antibodies

Are Th2 cytokines

Are virus proteins that interfere with activation of cytotoxic T cells

Inhibits virus replication by infected cells

60. A poikilothermic organism living in the Arctic would have, compared to that organism living in the temperate climate zone, a plasma membrane richer in

Cholesterol

Long chain fatty acid

Protein

Unsaturated fatty acid


61. Colchicine treated cells are arrested in

S phase

Prophase

G1 phase

Metaphase

62. The endosymbiotic origin of plastids from bacteria suggested by all of the following except

Antibiotic sensitivity of plastid ribosomes

Circular DNA in plastids

Introns in plastid DNA genes

Ribosome size in plastids

63. Which of the following are correct statements
P. All proteins destined for the peroxisomal matrix bind to a cytosolic receptor
Q. Zellweger syndrome is associated with impaired transport ofproteins into peroxisomal matrix
R. Peroxisomal targeting sequence may be C-terminal PTS1or N terminal PTS2
S. Peroxisomal targeting sequence is non cleavable

P,Q



P,R



64. Hair color in some animals can be black grey or white If a black and grey animal mate and produce three offspring, what is the probability that only one is grey

1/8

1/4

3/8

1/2

65. In the normal human being the concentration(s) of various antibodies in the serum in the order

IgM>IgA>IgG>IgE

IgG>IgA>IgM>IgE

IgE>IgG>IgM>IgA

IgA>IgM>IgE>IgG

66. The name of the process by which oil glands in mammalian skin secrete oil is

active transport

apocrine secretion

holocrine secretion

osmosis

67. In first stage of photosynthesis, light energy is used to

move water molecule

denature chlorophyll

split water

produce carbohydrate

68. Water molecule enter plant epidermal cells by

osmosis

active transport

translocation

transpiration

69. The muscle which is under involuntary control is

striated

smooth

skeletal

endothelial

70. Oxidation of fats and carbohydrate with in a cells would be an example of

metabolism

catabolism

biosynthesis

anabolism

71. What percentage of the atmosphere consist of carbon dioxide

0.03%







72. Ecological pyramids graphically represent trophic structure and function of an ecosystem. Which one of the following type of ecological pyramid is always upright

Pyramid of numbers

Pyramid of biomass

Pyramid of energy

All the above

73. Genes in a polycistronic operon are expressed with a

Single promoter

Double prolnoter

Many promoters

Promoter is not required for its expression


74. Which one of the following enzymes cannot carry a reversible reaction in the Citric Acid cycle

Citrate synthase

Succinate dehydrogenase

Fumarase

Aconitase

75. One of the following metabolites is not related to primary metabolism

Sucrose

Anthocyanin

Pyruvate

Phosphoglycerate