Exam Details
| Subject | medicinal chemistry – ii | |
| Paper | ||
| Exam / Course | b. pharmacy | |
| Department | ||
| Organization | solapur university | |
| Position | ||
| Exam Date | 09, May, 2017 | |
| City, State | andhra pradesh, solapur |
Question Paper
B.Pharmacy (Semester VII) Examination, 2017
MEDICINAL CHEMISTRY III
Day and Date Tuesday, 9-5-2017 Total Marks 80
Time 3.00 p.m. to 6.00 p.m.
1. Multiple Choice Question (16×1=16)
Piroxicam contain nucleus.
Purine 2 benzothiazine
Pyrazolidine Indole
is an xanthine alkaloid.
Papaverine Caffeine
Morphine All of above
not a proton pump inhibitor.
Omeprazole Lansoprazole
Domperidone Ranitidine
Estrogen, testosterone and progestin contain carbon in
steroidal nucleus.
18, 19, 21 19, 18, 21
21, 19, 18 19, 21, 18
Some adrenocorticoids are referred to as Δ corticoids because of
Additional double bond in ring
High amount of unsaturation in the molecule
Presence of one double bond in each ring
Absence of double bond in ring
Which of the following is mainly an anxiolytic drug
Chlorpromazine Lithium
Phenelzine Diazepam
Barbiturate is derivative of
Urea Alcohol
Opium None of above
Prednisone and prednisolone are the of cortisone and
hydrocortisone.
1-dehydro derivative 3-hydroxy derivative
2-hydroxy derivative All of above
One of the following is an ester
Morphine Nalorphine
Heroin Methadone
10) long acting barbiturate.
Phenobarbital Probarbital
Hexobarbital Thiopentane
11) MAO inhibitor.
Phenelzine Amitriptyline
Imipramine Nortriptyline
12) Phenylbutazone is an derivative of
Pyrazolidinedione N-arylanthranilic acid
Acetic acid derivative Aniline
13) xanthine oxidase inhibitor drugs.
Allopurinol Nimusulide
Indomethacin None of above
14) is an anabolic steroid.
Estrone Lynesterol
Prednisolone Oxymestrone
15) Phenytoin is synthesized from
Urea Benzil
a b None of above
16) not a morphine antagonist.
Nalorphine Naloxone
Naltrexone Levorphanol
2. Answer any four
Write synthesis of Pentobarbitol and Phenytoin.
Classify NSAID with example.
Explain modification on Morphine nucleus.
Note on oral contraceptive.
Explain COX-2 inhibitors drugs with examples.
3. Answer any four
Explain in detail Adrenal cortex hormones.
Add a note on drug used in gout disease.
Write structure, uses, chemical name of long acting barbiturate drug.
Explain drug used as CNS stimulant drug.
Note on TCA drug.
4. Answer any two
Explain how acid secreted in body and explain the development of cimetidine
as H2 antagonist.
Note on steroid and explain MOA and discuss nomenclature, numbering and
stereochemistry of it.
Classify hypnotic and sedative drug and write SAR of benzodiazepine.
5. Answer any two
Classify antihistaminic drug and explain SAR of H1 antagonistic drugs.
Classify anticonvulsant drug and explain SAR of barbiturates.
How inflammation produce in body and explain SAR of salisylic acid and aryl
acetic derivative
MEDICINAL CHEMISTRY III
Day and Date Tuesday, 9-5-2017 Total Marks 80
Time 3.00 p.m. to 6.00 p.m.
1. Multiple Choice Question (16×1=16)
Piroxicam contain nucleus.
Purine 2 benzothiazine
Pyrazolidine Indole
is an xanthine alkaloid.
Papaverine Caffeine
Morphine All of above
not a proton pump inhibitor.
Omeprazole Lansoprazole
Domperidone Ranitidine
Estrogen, testosterone and progestin contain carbon in
steroidal nucleus.
18, 19, 21 19, 18, 21
21, 19, 18 19, 21, 18
Some adrenocorticoids are referred to as Δ corticoids because of
Additional double bond in ring
High amount of unsaturation in the molecule
Presence of one double bond in each ring
Absence of double bond in ring
Which of the following is mainly an anxiolytic drug
Chlorpromazine Lithium
Phenelzine Diazepam
Barbiturate is derivative of
Urea Alcohol
Opium None of above
Prednisone and prednisolone are the of cortisone and
hydrocortisone.
1-dehydro derivative 3-hydroxy derivative
2-hydroxy derivative All of above
One of the following is an ester
Morphine Nalorphine
Heroin Methadone
10) long acting barbiturate.
Phenobarbital Probarbital
Hexobarbital Thiopentane
11) MAO inhibitor.
Phenelzine Amitriptyline
Imipramine Nortriptyline
12) Phenylbutazone is an derivative of
Pyrazolidinedione N-arylanthranilic acid
Acetic acid derivative Aniline
13) xanthine oxidase inhibitor drugs.
Allopurinol Nimusulide
Indomethacin None of above
14) is an anabolic steroid.
Estrone Lynesterol
Prednisolone Oxymestrone
15) Phenytoin is synthesized from
Urea Benzil
a b None of above
16) not a morphine antagonist.
Nalorphine Naloxone
Naltrexone Levorphanol
2. Answer any four
Write synthesis of Pentobarbitol and Phenytoin.
Classify NSAID with example.
Explain modification on Morphine nucleus.
Note on oral contraceptive.
Explain COX-2 inhibitors drugs with examples.
3. Answer any four
Explain in detail Adrenal cortex hormones.
Add a note on drug used in gout disease.
Write structure, uses, chemical name of long acting barbiturate drug.
Explain drug used as CNS stimulant drug.
Note on TCA drug.
4. Answer any two
Explain how acid secreted in body and explain the development of cimetidine
as H2 antagonist.
Note on steroid and explain MOA and discuss nomenclature, numbering and
stereochemistry of it.
Classify hypnotic and sedative drug and write SAR of benzodiazepine.
5. Answer any two
Classify antihistaminic drug and explain SAR of H1 antagonistic drugs.
Classify anticonvulsant drug and explain SAR of barbiturates.
How inflammation produce in body and explain SAR of salisylic acid and aryl
acetic derivative
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Subjects
- anatomy, physiology and health education – i
- anatomy, physiology and health education – ii
- biochemistry
- biochemistry – i
- biochemistry – ii
- biopharmaceutics
- biotechnology
- clinical pharmacology
- herbal technology
- human anatomy and physiology – i
- human anatomy and physiology – ii
- medicinal chemistry – i
- medicinal chemistry – ii
- medicinal chemistry – iv
- microbiology
- modern dispensing and hospital pharmacy
- novel drug delivery systems
- organic chemistry – i
- organic chemistry – ii
- organic chemistry – iii
- pathophysiology (new cbcs)
- pathophysiology and clinical biochemistry – i
- pathophysiology and clinical biochemistry – ii
- pharmaceutical analysis – i
- pharmaceutical analysis – ii
- pharmaceutical analysis – iv
- pharmaceutical analysis – v
- pharmaceutical analysis – vi
- pharmaceutical busines management
- pharmaceutical engineering
- pharmaceutical enginering
- pharmaceutical inorganic chemistry
- pharmaceutical jurisprudence
- pharmaceutical microbiology
- pharmaceutical organic chemistry – ii
- pharmaceutical organic chemistry –i
- pharmaceutics – i (new cbcs)
- pharmaceutics – i (old-cbcs pattern)
- pharmaceutics – ii
- pharmaceutics – iii
- pharmaceutics – iv
- pharmacognosy – i
- pharmacognosy – ii
- pharmacognosy – iii
- pharmacology – i (new) (cbcs pattern)
- pharmacology – ii
- pharmacology – ii (cgpa pattern)
- pharmacology – iv
- physical pharmaceutics – i
- physical pharmacy – i
- physical pharmacy – ii
- sterile dosage forms