Exam Details
| Subject | medicinal chemistry – ii | |
| Paper | ||
| Exam / Course | b. pharmacy | |
| Department | ||
| Organization | solapur university | |
| Position | ||
| Exam Date | March, 2018 | |
| City, State | andhra pradesh, solapur |
Question Paper
B.Pharm. (Semester VI) (CGPA) Examination, 2018
medicinal chemistry II
Day and Date Friday, 11-5-2018 Max. Marks 70
Time 10.30 a.m. to 1.30 p.m.
1. Multiple Choice Question (1×15=15)
Isoniazide inhibits
Xanthine oxidase GABA
Mycolase synthase Choline esterase
The long acting sulphonamide is
Sulphamethoxazole Sulphadiazine
Sulphacetamide Sulphadoxine
is used as Quinoline antibacterial agent.
Metronidazole Niclosamide
Norfloxacine Nimusulide
Identify which group present at C-4 position of sulphonamide.
Amino Nitro Methyl Acetyl
Griseofulvin shows action by interfering with
Mitosis Meiosis
Peptide synthesis Protein synthesis
Which of the following ring is present in Sulphamethoxazole
Pyridine Oxazole
Iso-oxazole Thiazole
Amantidine used as antiviral agent by inhibiting
Uncoating of the influenza RNA synthesis
Xanthine oxidase DNA gyrase
Cardiotoxicity is major drawbacks for use of anticancer drug.
Cisplatin Doxorubicine
Nitrosoureas 5-fu
Which one is alkylating agent
Thioguanin Mitomycine Tacrolimus Doxorubicine
10) drug inhibits DNA gyrase enzyme.
Sulphasalzine Sparfloxacine
Stavudine Trimethoprime
11) Mechanism of action of Tenofovir is
Uncoating inhibitor Reverse transcriptase inhibitor
Adsorption inhibitor Protease inhibitor
12) is a starting material for synthesis of Amantidine.
1-bromoadmantane Rimantidine
2-bromoadmantane Tromatidine
13) Chloroquine is derivatives of
8-aminoquinoline 9-aminoacridine
4-aminoquinoline 3-aminoquinoline
14) Which of the following drug is used in candidiasis
Griseofulvin Thioacetazone
Tolnaftate Tolbutamide
15) The sugar that is inherent in nucleic acid RNA and DNA is
Glucose Digitoxose Ribose Sucrose
2. Answer any five of the following questions
Discuss DOT therapy in anti T. B. treatment.
Explain the term "reverse transcriptase inhibitors".
Draw the structure, SAR and MOA of 5 FU.
What is combination therapy
Explain SAR and MOA of Nalidixic acid used as Quinoline antibacterial agent.
Describe viral replication process and classify with e.g.
3. Answer the following questions (3×10=30)
Outline synthesis and uses of chloroquine, acyclovir, amantidine, isoniazide.
Explain the life cycle of malarial parasite and classify anti malarial drugs with e.g.
Classify anti-neo plastic agent giving suitable e.g. Explain MOA of alkylating agent.
medicinal chemistry II
Day and Date Friday, 11-5-2018 Max. Marks 70
Time 10.30 a.m. to 1.30 p.m.
1. Multiple Choice Question (1×15=15)
Isoniazide inhibits
Xanthine oxidase GABA
Mycolase synthase Choline esterase
The long acting sulphonamide is
Sulphamethoxazole Sulphadiazine
Sulphacetamide Sulphadoxine
is used as Quinoline antibacterial agent.
Metronidazole Niclosamide
Norfloxacine Nimusulide
Identify which group present at C-4 position of sulphonamide.
Amino Nitro Methyl Acetyl
Griseofulvin shows action by interfering with
Mitosis Meiosis
Peptide synthesis Protein synthesis
Which of the following ring is present in Sulphamethoxazole
Pyridine Oxazole
Iso-oxazole Thiazole
Amantidine used as antiviral agent by inhibiting
Uncoating of the influenza RNA synthesis
Xanthine oxidase DNA gyrase
Cardiotoxicity is major drawbacks for use of anticancer drug.
Cisplatin Doxorubicine
Nitrosoureas 5-fu
Which one is alkylating agent
Thioguanin Mitomycine Tacrolimus Doxorubicine
10) drug inhibits DNA gyrase enzyme.
Sulphasalzine Sparfloxacine
Stavudine Trimethoprime
11) Mechanism of action of Tenofovir is
Uncoating inhibitor Reverse transcriptase inhibitor
Adsorption inhibitor Protease inhibitor
12) is a starting material for synthesis of Amantidine.
1-bromoadmantane Rimantidine
2-bromoadmantane Tromatidine
13) Chloroquine is derivatives of
8-aminoquinoline 9-aminoacridine
4-aminoquinoline 3-aminoquinoline
14) Which of the following drug is used in candidiasis
Griseofulvin Thioacetazone
Tolnaftate Tolbutamide
15) The sugar that is inherent in nucleic acid RNA and DNA is
Glucose Digitoxose Ribose Sucrose
2. Answer any five of the following questions
Discuss DOT therapy in anti T. B. treatment.
Explain the term "reverse transcriptase inhibitors".
Draw the structure, SAR and MOA of 5 FU.
What is combination therapy
Explain SAR and MOA of Nalidixic acid used as Quinoline antibacterial agent.
Describe viral replication process and classify with e.g.
3. Answer the following questions (3×10=30)
Outline synthesis and uses of chloroquine, acyclovir, amantidine, isoniazide.
Explain the life cycle of malarial parasite and classify anti malarial drugs with e.g.
Classify anti-neo plastic agent giving suitable e.g. Explain MOA of alkylating agent.
Other Question Papers
Subjects
- anatomy, physiology and health education – i
- anatomy, physiology and health education – ii
- biochemistry
- biochemistry – i
- biochemistry – ii
- biopharmaceutics
- biotechnology
- clinical pharmacology
- herbal technology
- human anatomy and physiology – i
- human anatomy and physiology – ii
- medicinal chemistry – i
- medicinal chemistry – ii
- medicinal chemistry – iv
- microbiology
- modern dispensing and hospital pharmacy
- novel drug delivery systems
- organic chemistry – i
- organic chemistry – ii
- organic chemistry – iii
- pathophysiology (new cbcs)
- pathophysiology and clinical biochemistry – i
- pathophysiology and clinical biochemistry – ii
- pharmaceutical analysis – i
- pharmaceutical analysis – ii
- pharmaceutical analysis – iv
- pharmaceutical analysis – v
- pharmaceutical analysis – vi
- pharmaceutical busines management
- pharmaceutical engineering
- pharmaceutical enginering
- pharmaceutical inorganic chemistry
- pharmaceutical jurisprudence
- pharmaceutical microbiology
- pharmaceutical organic chemistry – ii
- pharmaceutical organic chemistry –i
- pharmaceutics – i (new cbcs)
- pharmaceutics – i (old-cbcs pattern)
- pharmaceutics – ii
- pharmaceutics – iii
- pharmaceutics – iv
- pharmacognosy – i
- pharmacognosy – ii
- pharmacognosy – iii
- pharmacology – i (new) (cbcs pattern)
- pharmacology – ii
- pharmacology – ii (cgpa pattern)
- pharmacology – iv
- physical pharmaceutics – i
- physical pharmacy – i
- physical pharmacy – ii
- sterile dosage forms