Exam Details
| Subject | medicinal chemistry – i | |
| Paper | ||
| Exam / Course | b. pharmacy | |
| Department | ||
| Organization | solapur university | |
| Position | ||
| Exam Date | 09, May, 2017 | |
| City, State | andhra pradesh, solapur |
Question Paper
B.Pharm. (Semester (New CGPA) Examination, 2017
MEDICINAL CHEMISTRY I
Day and Date Tuesday, 9-5-2017 Total Marks 70
Time 10.30 a.m. to 1.30 p.m.
1. Multiple Choice Questions. (15×1=15)
Which step involved in phase I reaction
Oxidation Reduction
Hydrolysis All of above
In small concentration surfactant has ability to increase
Solubility Lipophilicity
Both a and b None of these
Diloxanide furoate is used in the treatment of amoebiasis caused by
Entamoeba histolytica Plasmodium ovale
Plasmodium vivax M.Tuberculosis
Niclosamide is used in the treatment of
Cestode disease Trematode disease
Nematode disease All of above
is the best agent in type II diabetic patient.
Atorvostatin Glipzide
Sulindac Furesamide
One of the following drug belonging to Biguanides class
Phenformin Tolbutamide
Acarbose Glibenclamide
Nitroimidazole derivatives are
Metronidazole Mebendazole
Albendazole All of above
Penicillin on acid degradation it gives
Penicillamine Penilloic acid
Penicillo-aldehyde All of above
The heterocyclic ring in furosemide is
Furan Thiophene
Pyrole Indole
10) Antibiotic when interact with calcium ion its chelates
Erythromycin Streptomycin
Tetracyclin Ampicillin
11) Glibenclamide belongs to the class
Sulfonyl Ureas Thiozolidinediones
Benzoic acid Biguanides
12) B-lactum antibiotic inhibit the synthesis by inhibiting
Peptoglycon Peptidoglycon
Polypeptide Peptidase
13) Mechanism of action of furosemide is
Inhibits carbonic anhydrase Osmotic diuretics
Inhibits Na-K-2Cl transporter Aldosterone antagonist
14) One of the following belongs to biguanides class
Phenformin Tolbutamide
Acarbose Glibenclamide
15) One of the following is glycopeptides antibiotics
Bleomycin Actinomycin D
Methramycin Pyrazinamide
SLR-D 23
2. Answer any five of the following questions.
Write a note on Drug Receptor interaction.
What happen when Tetracycline undergo epimerization, chelation, strong acid
and strong base.
Draw structure, chemical name, metabolism and synthesis of Metronidazole.
Write MOA and SAR of Penicillin.
Describe factors affecting drug metabolism.
Write in details of protein binding.
3. Answer any three of the following questions. (3×10=30)
What is Metabolism Write a note on Phase I reaction.
Write a note on Solubility and Hydrogen Bonding.
Write uses and synthesis of Mebendazole and Chlorpropamide.
Write MOA, SAR of carbonic acid anhydrase inhibitors with eg.
MEDICINAL CHEMISTRY I
Day and Date Tuesday, 9-5-2017 Total Marks 70
Time 10.30 a.m. to 1.30 p.m.
1. Multiple Choice Questions. (15×1=15)
Which step involved in phase I reaction
Oxidation Reduction
Hydrolysis All of above
In small concentration surfactant has ability to increase
Solubility Lipophilicity
Both a and b None of these
Diloxanide furoate is used in the treatment of amoebiasis caused by
Entamoeba histolytica Plasmodium ovale
Plasmodium vivax M.Tuberculosis
Niclosamide is used in the treatment of
Cestode disease Trematode disease
Nematode disease All of above
is the best agent in type II diabetic patient.
Atorvostatin Glipzide
Sulindac Furesamide
One of the following drug belonging to Biguanides class
Phenformin Tolbutamide
Acarbose Glibenclamide
Nitroimidazole derivatives are
Metronidazole Mebendazole
Albendazole All of above
Penicillin on acid degradation it gives
Penicillamine Penilloic acid
Penicillo-aldehyde All of above
The heterocyclic ring in furosemide is
Furan Thiophene
Pyrole Indole
10) Antibiotic when interact with calcium ion its chelates
Erythromycin Streptomycin
Tetracyclin Ampicillin
11) Glibenclamide belongs to the class
Sulfonyl Ureas Thiozolidinediones
Benzoic acid Biguanides
12) B-lactum antibiotic inhibit the synthesis by inhibiting
Peptoglycon Peptidoglycon
Polypeptide Peptidase
13) Mechanism of action of furosemide is
Inhibits carbonic anhydrase Osmotic diuretics
Inhibits Na-K-2Cl transporter Aldosterone antagonist
14) One of the following belongs to biguanides class
Phenformin Tolbutamide
Acarbose Glibenclamide
15) One of the following is glycopeptides antibiotics
Bleomycin Actinomycin D
Methramycin Pyrazinamide
SLR-D 23
2. Answer any five of the following questions.
Write a note on Drug Receptor interaction.
What happen when Tetracycline undergo epimerization, chelation, strong acid
and strong base.
Draw structure, chemical name, metabolism and synthesis of Metronidazole.
Write MOA and SAR of Penicillin.
Describe factors affecting drug metabolism.
Write in details of protein binding.
3. Answer any three of the following questions. (3×10=30)
What is Metabolism Write a note on Phase I reaction.
Write a note on Solubility and Hydrogen Bonding.
Write uses and synthesis of Mebendazole and Chlorpropamide.
Write MOA, SAR of carbonic acid anhydrase inhibitors with eg.
Other Question Papers
Subjects
- anatomy, physiology and health education – i
- anatomy, physiology and health education – ii
- biochemistry
- biochemistry – i
- biochemistry – ii
- biopharmaceutics
- biotechnology
- clinical pharmacology
- herbal technology
- human anatomy and physiology – i
- human anatomy and physiology – ii
- medicinal chemistry – i
- medicinal chemistry – ii
- medicinal chemistry – iv
- microbiology
- modern dispensing and hospital pharmacy
- novel drug delivery systems
- organic chemistry – i
- organic chemistry – ii
- organic chemistry – iii
- pathophysiology (new cbcs)
- pathophysiology and clinical biochemistry – i
- pathophysiology and clinical biochemistry – ii
- pharmaceutical analysis – i
- pharmaceutical analysis – ii
- pharmaceutical analysis – iv
- pharmaceutical analysis – v
- pharmaceutical analysis – vi
- pharmaceutical busines management
- pharmaceutical engineering
- pharmaceutical enginering
- pharmaceutical inorganic chemistry
- pharmaceutical jurisprudence
- pharmaceutical microbiology
- pharmaceutical organic chemistry – ii
- pharmaceutical organic chemistry –i
- pharmaceutics – i (new cbcs)
- pharmaceutics – i (old-cbcs pattern)
- pharmaceutics – ii
- pharmaceutics – iii
- pharmaceutics – iv
- pharmacognosy – i
- pharmacognosy – ii
- pharmacognosy – iii
- pharmacology – i (new) (cbcs pattern)
- pharmacology – ii
- pharmacology – ii (cgpa pattern)
- pharmacology – iv
- physical pharmaceutics – i
- physical pharmacy – i
- physical pharmacy – ii
- sterile dosage forms