Exam Details
| Subject | medicinal chemistry – i | |
| Paper | ||
| Exam / Course | b. pharmacy | |
| Department | ||
| Organization | solapur university | |
| Position | ||
| Exam Date | March, 2018 | |
| City, State | andhra pradesh, solapur |
Question Paper
B.Pharm. (Semester (CGPA) Examination, 2018
medicinal chemistry I
Day and Date Tuesday, 8-5-2018 Max. Marks 70
Time 10.30 a.m. to 1.30 p.m.
1. Multiple Choice Questions (15×1=15)
The metabolism of drug involves
Ist order IInd order
Zero order Pseudo order
One of the following belongs to biguanides class
Phenformin Tolbutamide
Glibenclamide Acarbose
For non-volatile drug according to ferguson principle relative super saturation
St/so Pt/po
So/st None
Tetracycline undergo epimerization at C-4 between pH-4 and 8 to give
Isotetracycline Epitetracycline
Nortetracycline None of these
Niclosamide is used in the treatment of
Cestode disease Nematode disease
Trematode disease All of the above
drug inhibits protein synthesis.
Emetine Acetazolamide
Quinine Paracetamol
Metronidazole binds to
DNA RNA
Cytoplasm None of these
is the third generation cephalosporin.
Cefotaxime Cefaclor
Cefoxitin None of these
Identify the high celling diuretics of below
Mannitol Furosemide
Spirinolactone Acetazolamide
10) Hydrochlorothiazide is synthesized from
3-chloroaniline 5-chloroaniline
Aniline None of these
11) used in luminal amoebicides.
Diloxanide furoate Emetine
Digitalis Aspirin
12) The heterocyclic ring is present in thiabendazole is
Benthiazole Thiazole
Benzimidazole Furan
13) Penicillin on degradation in acid medium forms
Penicillamine Penilloic acid
Penicillo-aldehyde All
14) Primary site of action of thiazide diuretics in the nephron is
Proximal tubule Loop of henle
Distal tubule Convulated tubule
15) One of the following drug is belongs to Carbonic Anhydrase inhibitors class
Spironlactone Mannitol
Methazolamide Xipamide
2. Answer any five of the following questions.
Write a note on Hydrogen bonding.
Explain different theories of receptors.
Classify anti-amoebic agents. Explain role of azoles in amoebiasis.
Explain "Sulphonylureaes as oral hypoglycemic agent".
Classify diuretics. Write structure, MOA and uses of Furocemide.
Explain anthelmintic agent in GIT nematode infection.
3. Answer any three of the following questions. (3×10=30)
Write a different forces involved in drug receptor interaction.
Explain in detail on Phase I Metabolism process.
Outline the synthesis and uses of Niclosamide, Metronidazole, Hydrochlorthiazide.
Discuss conversion of Tetracycline to
4-epitetracyclin by epimerization,
Anhydrotetracyclin,
Isotetracyclin,
Chelate comp
Give MOA of Tetracycline.
medicinal chemistry I
Day and Date Tuesday, 8-5-2018 Max. Marks 70
Time 10.30 a.m. to 1.30 p.m.
1. Multiple Choice Questions (15×1=15)
The metabolism of drug involves
Ist order IInd order
Zero order Pseudo order
One of the following belongs to biguanides class
Phenformin Tolbutamide
Glibenclamide Acarbose
For non-volatile drug according to ferguson principle relative super saturation
St/so Pt/po
So/st None
Tetracycline undergo epimerization at C-4 between pH-4 and 8 to give
Isotetracycline Epitetracycline
Nortetracycline None of these
Niclosamide is used in the treatment of
Cestode disease Nematode disease
Trematode disease All of the above
drug inhibits protein synthesis.
Emetine Acetazolamide
Quinine Paracetamol
Metronidazole binds to
DNA RNA
Cytoplasm None of these
is the third generation cephalosporin.
Cefotaxime Cefaclor
Cefoxitin None of these
Identify the high celling diuretics of below
Mannitol Furosemide
Spirinolactone Acetazolamide
10) Hydrochlorothiazide is synthesized from
3-chloroaniline 5-chloroaniline
Aniline None of these
11) used in luminal amoebicides.
Diloxanide furoate Emetine
Digitalis Aspirin
12) The heterocyclic ring is present in thiabendazole is
Benthiazole Thiazole
Benzimidazole Furan
13) Penicillin on degradation in acid medium forms
Penicillamine Penilloic acid
Penicillo-aldehyde All
14) Primary site of action of thiazide diuretics in the nephron is
Proximal tubule Loop of henle
Distal tubule Convulated tubule
15) One of the following drug is belongs to Carbonic Anhydrase inhibitors class
Spironlactone Mannitol
Methazolamide Xipamide
2. Answer any five of the following questions.
Write a note on Hydrogen bonding.
Explain different theories of receptors.
Classify anti-amoebic agents. Explain role of azoles in amoebiasis.
Explain "Sulphonylureaes as oral hypoglycemic agent".
Classify diuretics. Write structure, MOA and uses of Furocemide.
Explain anthelmintic agent in GIT nematode infection.
3. Answer any three of the following questions. (3×10=30)
Write a different forces involved in drug receptor interaction.
Explain in detail on Phase I Metabolism process.
Outline the synthesis and uses of Niclosamide, Metronidazole, Hydrochlorthiazide.
Discuss conversion of Tetracycline to
4-epitetracyclin by epimerization,
Anhydrotetracyclin,
Isotetracyclin,
Chelate comp
Give MOA of Tetracycline.
Other Question Papers
Subjects
- anatomy, physiology and health education – i
- anatomy, physiology and health education – ii
- biochemistry
- biochemistry – i
- biochemistry – ii
- biopharmaceutics
- biotechnology
- clinical pharmacology
- herbal technology
- human anatomy and physiology – i
- human anatomy and physiology – ii
- medicinal chemistry – i
- medicinal chemistry – ii
- medicinal chemistry – iv
- microbiology
- modern dispensing and hospital pharmacy
- novel drug delivery systems
- organic chemistry – i
- organic chemistry – ii
- organic chemistry – iii
- pathophysiology (new cbcs)
- pathophysiology and clinical biochemistry – i
- pathophysiology and clinical biochemistry – ii
- pharmaceutical analysis – i
- pharmaceutical analysis – ii
- pharmaceutical analysis – iv
- pharmaceutical analysis – v
- pharmaceutical analysis – vi
- pharmaceutical busines management
- pharmaceutical engineering
- pharmaceutical enginering
- pharmaceutical inorganic chemistry
- pharmaceutical jurisprudence
- pharmaceutical microbiology
- pharmaceutical organic chemistry – ii
- pharmaceutical organic chemistry –i
- pharmaceutics – i (new cbcs)
- pharmaceutics – i (old-cbcs pattern)
- pharmaceutics – ii
- pharmaceutics – iii
- pharmaceutics – iv
- pharmacognosy – i
- pharmacognosy – ii
- pharmacognosy – iii
- pharmacology – i (new) (cbcs pattern)
- pharmacology – ii
- pharmacology – ii (cgpa pattern)
- pharmacology – iv
- physical pharmaceutics – i
- physical pharmacy – i
- physical pharmacy – ii
- sterile dosage forms