Exam Details
| Subject | medicinal chemistry – i | |
| Paper | ||
| Exam / Course | b. pharmacy | |
| Department | ||
| Organization | solapur university | |
| Position | ||
| Exam Date | October, 2018 | |
| City, State | andhra pradesh, solapur |
Question Paper
B.Pharm (Sem. (New CBCS) Examination, 2018
Medicinal CHEMISTRY i
Day and Date Wednesday, 12-12-2018 Max. Marks 70
Time 10.30 a.m. to 1.30 p.m.
1. Multiple choice questions (15×1 =15 Marks)
Metabolism is mainly observed in
Liver Heart
Brain None of these
Chloropropamide is synthesized from
Chlorobenzene Benzene
Aniline None of these
For non-volatile drug according to ferguson principle relative super
saturation
St/so Pt/po So/st None
Metronidazole having efficacy due to group, this participates in
endogenous reduction process.
Nitro Amino
Alkyl None of these
Mannitol is showing action by Phenomenon.
Osmosis Reverse osmosis
Both and None of these
drug inhibits protein synthesis.
Emetine Acetazolamide
Quinine Paracetamol
Paton and Rang proposed theory.
Occupation theory Rate theory
Induced fit theory Activation Aggregation theory
B-lactam antibiotics inhibit the synthesis by inhibiting
Peptoglycan Peptidoglycan
Polypeptide Peptidase
Identify the high celling diuretics of below
Mannitol Furosemide
Spirinolactone Acetazolamide
10) drug is not effective against systemic amoebiasis.
Metronidazole Chloroquine
Diloxanide furoate Dihydroemetin
11) Niclosamide is used in the treatment of
Cestode Nematode
Trematode All of the above
12) The heterocyclic ring is present in thiabendazole is
Benthiazale Thiazole
Benzimidazole Furan
13) Penicillin on degradation in alkaline medium forms
Penillic acid Penicillic acid
Penicilloic acid Penicilenic acid
14) Bacampacillin is
Active drug Prodrug
Active metabolite None of these
15) One of the following drug is belongs to Carbonic Anhydrase Inhibitors
class
Spironlactone Mannitol
Methazolamide Xipamide
Set P
*SRLTV33* SLR-TV 33
2. Answer any five of the following questions
Write a note on Bio-isosterism.
Discuss in details of drug receptor interaction.
Write SAR and MOA of sulphonyl urease.
Write the synthesis of Niclosamide Mebendazole.
Draw the structure, chemical name of Metronidazole, Niridazole, Mebendazole.
Define Diuretics. Explain in details of Thiazide Diuretics.
3. Answer any three of the following questions (3×10=30)
Define and classify antibiotics with suitable e.g. Write MOA and SAR of
B-lactam antibiotics.
Write a note on receptor and biological response.
List out the Phase I and Phase II metabolism process. Explain in details
Phase II reaction.
Discuss conversion to Tetracycline to
4-epitetracyclin by epimerization
Anhydrotetracyclin
Isotetracyclin
Chelate comp
Give MOA of Tetracycline.
Medicinal CHEMISTRY i
Day and Date Wednesday, 12-12-2018 Max. Marks 70
Time 10.30 a.m. to 1.30 p.m.
1. Multiple choice questions (15×1 =15 Marks)
Metabolism is mainly observed in
Liver Heart
Brain None of these
Chloropropamide is synthesized from
Chlorobenzene Benzene
Aniline None of these
For non-volatile drug according to ferguson principle relative super
saturation
St/so Pt/po So/st None
Metronidazole having efficacy due to group, this participates in
endogenous reduction process.
Nitro Amino
Alkyl None of these
Mannitol is showing action by Phenomenon.
Osmosis Reverse osmosis
Both and None of these
drug inhibits protein synthesis.
Emetine Acetazolamide
Quinine Paracetamol
Paton and Rang proposed theory.
Occupation theory Rate theory
Induced fit theory Activation Aggregation theory
B-lactam antibiotics inhibit the synthesis by inhibiting
Peptoglycan Peptidoglycan
Polypeptide Peptidase
Identify the high celling diuretics of below
Mannitol Furosemide
Spirinolactone Acetazolamide
10) drug is not effective against systemic amoebiasis.
Metronidazole Chloroquine
Diloxanide furoate Dihydroemetin
11) Niclosamide is used in the treatment of
Cestode Nematode
Trematode All of the above
12) The heterocyclic ring is present in thiabendazole is
Benthiazale Thiazole
Benzimidazole Furan
13) Penicillin on degradation in alkaline medium forms
Penillic acid Penicillic acid
Penicilloic acid Penicilenic acid
14) Bacampacillin is
Active drug Prodrug
Active metabolite None of these
15) One of the following drug is belongs to Carbonic Anhydrase Inhibitors
class
Spironlactone Mannitol
Methazolamide Xipamide
Set P
*SRLTV33* SLR-TV 33
2. Answer any five of the following questions
Write a note on Bio-isosterism.
Discuss in details of drug receptor interaction.
Write SAR and MOA of sulphonyl urease.
Write the synthesis of Niclosamide Mebendazole.
Draw the structure, chemical name of Metronidazole, Niridazole, Mebendazole.
Define Diuretics. Explain in details of Thiazide Diuretics.
3. Answer any three of the following questions (3×10=30)
Define and classify antibiotics with suitable e.g. Write MOA and SAR of
B-lactam antibiotics.
Write a note on receptor and biological response.
List out the Phase I and Phase II metabolism process. Explain in details
Phase II reaction.
Discuss conversion to Tetracycline to
4-epitetracyclin by epimerization
Anhydrotetracyclin
Isotetracyclin
Chelate comp
Give MOA of Tetracycline.
Other Question Papers
Subjects
- anatomy, physiology and health education – i
- anatomy, physiology and health education – ii
- biochemistry
- biochemistry – i
- biochemistry – ii
- biopharmaceutics
- biotechnology
- clinical pharmacology
- herbal technology
- human anatomy and physiology – i
- human anatomy and physiology – ii
- medicinal chemistry – i
- medicinal chemistry – ii
- medicinal chemistry – iv
- microbiology
- modern dispensing and hospital pharmacy
- novel drug delivery systems
- organic chemistry – i
- organic chemistry – ii
- organic chemistry – iii
- pathophysiology (new cbcs)
- pathophysiology and clinical biochemistry – i
- pathophysiology and clinical biochemistry – ii
- pharmaceutical analysis – i
- pharmaceutical analysis – ii
- pharmaceutical analysis – iv
- pharmaceutical analysis – v
- pharmaceutical analysis – vi
- pharmaceutical busines management
- pharmaceutical engineering
- pharmaceutical enginering
- pharmaceutical inorganic chemistry
- pharmaceutical jurisprudence
- pharmaceutical microbiology
- pharmaceutical organic chemistry – ii
- pharmaceutical organic chemistry –i
- pharmaceutics – i (new cbcs)
- pharmaceutics – i (old-cbcs pattern)
- pharmaceutics – ii
- pharmaceutics – iii
- pharmaceutics – iv
- pharmacognosy – i
- pharmacognosy – ii
- pharmacognosy – iii
- pharmacology – i (new) (cbcs pattern)
- pharmacology – ii
- pharmacology – ii (cgpa pattern)
- pharmacology – iv
- physical pharmaceutics – i
- physical pharmacy – i
- physical pharmacy – ii
- sterile dosage forms