Exam Details
| Subject | medicinal chemistry – iv | |
| Paper | ||
| Exam / Course | b. pharmacy | |
| Department | ||
| Organization | solapur university | |
| Position | ||
| Exam Date | March, 2018 | |
| City, State | andhra pradesh, solapur |
Question Paper
B.Pharm. (Semester VIII) (New CGPA Pattern) Examination, 2018
medicinal chemistry IV
Day and Date Friday, 11-05-2018 Max. Marks 70
Time 3.00 p.m. to 6.00 p.m.
1. Multiple Choice Questions (1×15=15)
Binding of quaternary nitrogen of Ach has been described on enzyme.
Anionic site Cationic site Electronic None of these
produces metabolism of Acetylcholine.
Molindone Acetylcholine esterase
Metyrosine Naltrexone
The drug which inhibits ACE is
Captopril Verapamil Atenolol Reserpine
is membrane stabilizing agent.
Naproxin Digoxin Atenolol Quinidine
drug irreversibly inhibits Acetylcholine esterase.
Hyoscine α-naphthol Isoflurophate Reserpine
is a ganglionic blocking agent.
Hyoscine Hyoscyamine
Tropine Mecamylamine
is calcium channel blocker.
Hydralazine Nifedipine Propranolol Provastatin
is HMG COA reductase inhibitor.
Atorvastatin Atenolol Adrenaline Enalapril
Papaverine is inhibitor of
MAO ACE
Phosphodiesterase None of these
10) In Pilocarpine, there is
Imidazole and Furan moiety Pyridine and Furan moiety
Imidazole and Pyran moiety Pyridine and Thiophene moiety
11) Prazocin contains which of the following rings
Piperazinyl Quinoxaline Piperazinyl quinazoline
Pyridyl quinoxaline Pyridyl quinazolines
12) drug used as Nitro vasodilator.
Amlodipine Nitroglycerin Salbutamol Procanamide
13) drug used as positive inotropic agent.
Amlodipine Guanethidine Digitalis Benzthiazole
14) is not QSAR parameter.
Lipophilic Electronic Steric Aliphatic
15) is adrenergic receptor antagonist.
Cholesterol Amiodarone Prazocin Nicotine
2. Answer any five of the following questions
Classify antihyperlipidemic drugs. Explain HMG CoA reducatase inhibitors.
Classify adrenergic blocking agents. Give SAR of β-adrenergic receptor antagonist.
Outline the synthesis of Methyldopa and Salbutamol.
Write a note on Free Wilson analysis.
Explain SAR, Chemistry and MOA of Cardiac glycoside.
Explain neuromuscular and ganglionic blocking agents.
3. Answer any three of the following questions (10×3=30)
Enlist varies QSAR parameters. Explain in brief lipophilic, electronic and steric parameters of QSAR.
Classify cholinergic agents. Write SAR, biosynthesis and metabolism of Acetylcholine.
Explain biosynthesis and metabolism of Norepinephrine. Write SAR of adrenergic agonist and drug affecting catecholamine biosynthesis.
Classify Antihypertensive agent. Explain in detail ACE inhibitors.
medicinal chemistry IV
Day and Date Friday, 11-05-2018 Max. Marks 70
Time 3.00 p.m. to 6.00 p.m.
1. Multiple Choice Questions (1×15=15)
Binding of quaternary nitrogen of Ach has been described on enzyme.
Anionic site Cationic site Electronic None of these
produces metabolism of Acetylcholine.
Molindone Acetylcholine esterase
Metyrosine Naltrexone
The drug which inhibits ACE is
Captopril Verapamil Atenolol Reserpine
is membrane stabilizing agent.
Naproxin Digoxin Atenolol Quinidine
drug irreversibly inhibits Acetylcholine esterase.
Hyoscine α-naphthol Isoflurophate Reserpine
is a ganglionic blocking agent.
Hyoscine Hyoscyamine
Tropine Mecamylamine
is calcium channel blocker.
Hydralazine Nifedipine Propranolol Provastatin
is HMG COA reductase inhibitor.
Atorvastatin Atenolol Adrenaline Enalapril
Papaverine is inhibitor of
MAO ACE
Phosphodiesterase None of these
10) In Pilocarpine, there is
Imidazole and Furan moiety Pyridine and Furan moiety
Imidazole and Pyran moiety Pyridine and Thiophene moiety
11) Prazocin contains which of the following rings
Piperazinyl Quinoxaline Piperazinyl quinazoline
Pyridyl quinoxaline Pyridyl quinazolines
12) drug used as Nitro vasodilator.
Amlodipine Nitroglycerin Salbutamol Procanamide
13) drug used as positive inotropic agent.
Amlodipine Guanethidine Digitalis Benzthiazole
14) is not QSAR parameter.
Lipophilic Electronic Steric Aliphatic
15) is adrenergic receptor antagonist.
Cholesterol Amiodarone Prazocin Nicotine
2. Answer any five of the following questions
Classify antihyperlipidemic drugs. Explain HMG CoA reducatase inhibitors.
Classify adrenergic blocking agents. Give SAR of β-adrenergic receptor antagonist.
Outline the synthesis of Methyldopa and Salbutamol.
Write a note on Free Wilson analysis.
Explain SAR, Chemistry and MOA of Cardiac glycoside.
Explain neuromuscular and ganglionic blocking agents.
3. Answer any three of the following questions (10×3=30)
Enlist varies QSAR parameters. Explain in brief lipophilic, electronic and steric parameters of QSAR.
Classify cholinergic agents. Write SAR, biosynthesis and metabolism of Acetylcholine.
Explain biosynthesis and metabolism of Norepinephrine. Write SAR of adrenergic agonist and drug affecting catecholamine biosynthesis.
Classify Antihypertensive agent. Explain in detail ACE inhibitors.
Other Question Papers
Subjects
- anatomy, physiology and health education – i
- anatomy, physiology and health education – ii
- biochemistry
- biochemistry – i
- biochemistry – ii
- biopharmaceutics
- biotechnology
- clinical pharmacology
- herbal technology
- human anatomy and physiology – i
- human anatomy and physiology – ii
- medicinal chemistry – i
- medicinal chemistry – ii
- medicinal chemistry – iv
- microbiology
- modern dispensing and hospital pharmacy
- novel drug delivery systems
- organic chemistry – i
- organic chemistry – ii
- organic chemistry – iii
- pathophysiology (new cbcs)
- pathophysiology and clinical biochemistry – i
- pathophysiology and clinical biochemistry – ii
- pharmaceutical analysis – i
- pharmaceutical analysis – ii
- pharmaceutical analysis – iv
- pharmaceutical analysis – v
- pharmaceutical analysis – vi
- pharmaceutical busines management
- pharmaceutical engineering
- pharmaceutical enginering
- pharmaceutical inorganic chemistry
- pharmaceutical jurisprudence
- pharmaceutical microbiology
- pharmaceutical organic chemistry – ii
- pharmaceutical organic chemistry –i
- pharmaceutics – i (new cbcs)
- pharmaceutics – i (old-cbcs pattern)
- pharmaceutics – ii
- pharmaceutics – iii
- pharmaceutics – iv
- pharmacognosy – i
- pharmacognosy – ii
- pharmacognosy – iii
- pharmacology – i (new) (cbcs pattern)
- pharmacology – ii
- pharmacology – ii (cgpa pattern)
- pharmacology – iv
- physical pharmaceutics – i
- physical pharmacy – i
- physical pharmacy – ii
- sterile dosage forms