Exam Details
| Subject | pharmaceutical analysis – v | |
| Paper | ||
| Exam / Course | b. pharmacy | |
| Department | ||
| Organization | solapur university | |
| Position | ||
| Exam Date | March, 2018 | |
| City, State | andhra pradesh, solapur |
Question Paper
B.Pharmacy (Semester VII) (CGPA) Examination, 2018
Pharmaceutical Analysis V
Day and Date Saturday, 12-5-2018 Total Marks 70
Time 3.00 p.m. to 6.00 p.m.
I. Multiple choice questions (15×1=15)
In gradient elution technique which property of mobile phase is most important
Viscosity Boiling point Polarity Specific gravity
Particle size of adsorbent should be in the range of mesh in Column chromatography.
100-200 250-350
<50 None of the above
In wet packing method of column is serious issue.
Clarity of column Air bubble
Dryness of bed Column breaking
In TLC is added in order to enhance adhesion of adsorbent over glass.
Sodium sulfate Copper sulfate
Ferrous sulfate Calcium sulfate
In Chromatography eluent moves against the gravity.
TLC Column
Radiant paper Descending paper
Paper chromatography is influenced by
Adsorption Partition
Ion exchange Affinity
In flame ionization detectors is measured.
Resistance Melting point
Current Absorbance
P.T.O.
Set P
SLR-TA 47 *SLRTA47*
In HPLC terminology, if capacity factor it is interpreted as separation.
High Moderate Very high No clear cut
Hydrogen bonding interactions between mobile and stationary phases are not seen in
HPLC Column TLC GLC
10) In ODS columns in HPLC, use of less polar mobile phase will influence RT
Shorten RT Prolong RT
No influence on RT None
11) In which of HPLC detector, compound loses its chemical structure
RI detector Mass spectrometers
UV visible Fluorescence
12) Cation exchange resins comprises
Neutral groups Basic groups
Acidic groups None
13) In the copolymerization of Styrene and divinyl benzene, is employed.
Triethyl amine Formaline
NaOH Benzoyl peroxide
14) Ninhydrin is used to visualize
Amino acids Alkaloids
Flavanoids Reducing sugars
15) Carrier gas is a component of
HPLC Ion exchange
Column Gas chromatography
II. Answer any five
Define chromatography and classify in detail with examples.
Enlist the detector of HPLC and explain with neat figure the two detectors used in HPLC.
List out different types of paper chromatographic techniques and explain any two.
Set P
*SLRTA47* SLR-TA 47
Explain different techniques of preparation of TLC plates.
Explain both dry and wet packing of column chromatography.
Define the terminologies
Retention time
Retention volume
Visualizing agent
Gradient elution
Partition coefficient.
III. Answer any three (3×10=30)
With neat labeled diagram of GC, explain columns and detectors used in GC, explain at list two in each.
What do you mean by ion exchange chromatography. Which are the type of ion exchange resins available and explain the preparation of cation and anion exchange resins with chemical reactions.
Write a note on
HETP and
Factors affecting Rf.
Explain different developmental techniques involved in thin layer chromatography. Also write a note on gel chromatography.
Pharmaceutical Analysis V
Day and Date Saturday, 12-5-2018 Total Marks 70
Time 3.00 p.m. to 6.00 p.m.
I. Multiple choice questions (15×1=15)
In gradient elution technique which property of mobile phase is most important
Viscosity Boiling point Polarity Specific gravity
Particle size of adsorbent should be in the range of mesh in Column chromatography.
100-200 250-350
<50 None of the above
In wet packing method of column is serious issue.
Clarity of column Air bubble
Dryness of bed Column breaking
In TLC is added in order to enhance adhesion of adsorbent over glass.
Sodium sulfate Copper sulfate
Ferrous sulfate Calcium sulfate
In Chromatography eluent moves against the gravity.
TLC Column
Radiant paper Descending paper
Paper chromatography is influenced by
Adsorption Partition
Ion exchange Affinity
In flame ionization detectors is measured.
Resistance Melting point
Current Absorbance
P.T.O.
Set P
SLR-TA 47 *SLRTA47*
In HPLC terminology, if capacity factor it is interpreted as separation.
High Moderate Very high No clear cut
Hydrogen bonding interactions between mobile and stationary phases are not seen in
HPLC Column TLC GLC
10) In ODS columns in HPLC, use of less polar mobile phase will influence RT
Shorten RT Prolong RT
No influence on RT None
11) In which of HPLC detector, compound loses its chemical structure
RI detector Mass spectrometers
UV visible Fluorescence
12) Cation exchange resins comprises
Neutral groups Basic groups
Acidic groups None
13) In the copolymerization of Styrene and divinyl benzene, is employed.
Triethyl amine Formaline
NaOH Benzoyl peroxide
14) Ninhydrin is used to visualize
Amino acids Alkaloids
Flavanoids Reducing sugars
15) Carrier gas is a component of
HPLC Ion exchange
Column Gas chromatography
II. Answer any five
Define chromatography and classify in detail with examples.
Enlist the detector of HPLC and explain with neat figure the two detectors used in HPLC.
List out different types of paper chromatographic techniques and explain any two.
Set P
*SLRTA47* SLR-TA 47
Explain different techniques of preparation of TLC plates.
Explain both dry and wet packing of column chromatography.
Define the terminologies
Retention time
Retention volume
Visualizing agent
Gradient elution
Partition coefficient.
III. Answer any three (3×10=30)
With neat labeled diagram of GC, explain columns and detectors used in GC, explain at list two in each.
What do you mean by ion exchange chromatography. Which are the type of ion exchange resins available and explain the preparation of cation and anion exchange resins with chemical reactions.
Write a note on
HETP and
Factors affecting Rf.
Explain different developmental techniques involved in thin layer chromatography. Also write a note on gel chromatography.
Other Question Papers
Subjects
- anatomy, physiology and health education – i
- anatomy, physiology and health education – ii
- biochemistry
- biochemistry – i
- biochemistry – ii
- biopharmaceutics
- biotechnology
- clinical pharmacology
- herbal technology
- human anatomy and physiology – i
- human anatomy and physiology – ii
- medicinal chemistry – i
- medicinal chemistry – ii
- medicinal chemistry – iv
- microbiology
- modern dispensing and hospital pharmacy
- novel drug delivery systems
- organic chemistry – i
- organic chemistry – ii
- organic chemistry – iii
- pathophysiology (new cbcs)
- pathophysiology and clinical biochemistry – i
- pathophysiology and clinical biochemistry – ii
- pharmaceutical analysis – i
- pharmaceutical analysis – ii
- pharmaceutical analysis – iv
- pharmaceutical analysis – v
- pharmaceutical analysis – vi
- pharmaceutical busines management
- pharmaceutical engineering
- pharmaceutical enginering
- pharmaceutical inorganic chemistry
- pharmaceutical jurisprudence
- pharmaceutical microbiology
- pharmaceutical organic chemistry – ii
- pharmaceutical organic chemistry –i
- pharmaceutics – i (new cbcs)
- pharmaceutics – i (old-cbcs pattern)
- pharmaceutics – ii
- pharmaceutics – iii
- pharmaceutics – iv
- pharmacognosy – i
- pharmacognosy – ii
- pharmacognosy – iii
- pharmacology – i (new) (cbcs pattern)
- pharmacology – ii
- pharmacology – ii (cgpa pattern)
- pharmacology – iv
- physical pharmaceutics – i
- physical pharmacy – i
- physical pharmacy – ii
- sterile dosage forms