Exam Details
| Subject | biopharmaceutics | |
| Paper | ||
| Exam / Course | b. pharmacy | |
| Department | ||
| Organization | solapur university | |
| Position | ||
| Exam Date | October, 2018 | |
| City, State | andhra pradesh, solapur |
Question Paper
B.Pharm. (Semester Examination, 2018
biopharmaceutics
(New CBCS Pattern)
Day and Date Monday, 10-12-2018 Total Marks 70
Time 10.30 a.m. to 1.30 p.m.
1. Multiple choice questions (1×15=15)
Pore transport drug absorption mechanism is also called as
Convective transport Bulk flow
Filtration All of these
Permeability is rate limiting step in absorption for which of following class
of drug
I III
II IV
is also called Tamoxifen binding site.
Site-III Site-I
Site-II Site-IV
Which of following globulin binds to Antigens
α1 β1 γ α2
By using which compound, we determine Active tubular Secretion of
kidney.
PAH Iodopyracet
Both and Creatinine
For both urine and bile excretion, drugs molecular weight should be
Daltons.
Less than 300 More than 500
300-500 All of these
Cmax value depends on
Dose Administered Rate of adsorption
Rate of Elimination All of these
P.T.O.
Seat
No. Set P
Set P
SLR-TV 32 *SLRTV32*
Synonym for compartment models is
Empirical model Realistic model
Psychological model Both and
pH of urine varies between
4.5 to 7.5 2.5 to 5.5
3.5 to 7.5 7.5 to 9.5
10) Which of following is primary parameter
Vd Clearance
t½ Both and
11) Volume of fluid cleared of unchanged drug per unit time is called
Clearance
Elimination
Volume of distribution
None of the above
12) is poorly perfused organ.
Brain Muscle
Bone Liver
13) Digitoxin binding site of Albumin is known as
Site I Site II
Site III Site IV
14) Elimination process having which of following processes
Excretion
Biotransformation
Distribution
None of the above
15) A agent that causes toxic effects on foetus called as
Teratogen
Allergen
Antigen
Both and
2. Solve any five
How pharmaco-technical factors affected on gastrointestinal drug absorption
Write in detail about BCFB and BPB barriers.
Explain binding of drug to HSA and globulins.
Describe salivary excretion as one of non-renal route of drug excretion with
suitable example.
Define non-linear pharmacokinetics and explain in brief causes of
Non-linearity.
Write a note on film theory as one of dissolution mechanism.
3. Solve any three (10×3=30)
What is mean by Pharmacokinetics model Classify and explain various
pharmacokinetic and pharmacodynamic parameters in detail.
Write a detailed note on one-compartment open model intravenous infusion.
Explain in detail various mechanism of drug absorption with suitable
examples.
Write detail various factors affected on renal excretion of drug.
biopharmaceutics
(New CBCS Pattern)
Day and Date Monday, 10-12-2018 Total Marks 70
Time 10.30 a.m. to 1.30 p.m.
1. Multiple choice questions (1×15=15)
Pore transport drug absorption mechanism is also called as
Convective transport Bulk flow
Filtration All of these
Permeability is rate limiting step in absorption for which of following class
of drug
I III
II IV
is also called Tamoxifen binding site.
Site-III Site-I
Site-II Site-IV
Which of following globulin binds to Antigens
α1 β1 γ α2
By using which compound, we determine Active tubular Secretion of
kidney.
PAH Iodopyracet
Both and Creatinine
For both urine and bile excretion, drugs molecular weight should be
Daltons.
Less than 300 More than 500
300-500 All of these
Cmax value depends on
Dose Administered Rate of adsorption
Rate of Elimination All of these
P.T.O.
Seat
No. Set P
Set P
SLR-TV 32 *SLRTV32*
Synonym for compartment models is
Empirical model Realistic model
Psychological model Both and
pH of urine varies between
4.5 to 7.5 2.5 to 5.5
3.5 to 7.5 7.5 to 9.5
10) Which of following is primary parameter
Vd Clearance
t½ Both and
11) Volume of fluid cleared of unchanged drug per unit time is called
Clearance
Elimination
Volume of distribution
None of the above
12) is poorly perfused organ.
Brain Muscle
Bone Liver
13) Digitoxin binding site of Albumin is known as
Site I Site II
Site III Site IV
14) Elimination process having which of following processes
Excretion
Biotransformation
Distribution
None of the above
15) A agent that causes toxic effects on foetus called as
Teratogen
Allergen
Antigen
Both and
2. Solve any five
How pharmaco-technical factors affected on gastrointestinal drug absorption
Write in detail about BCFB and BPB barriers.
Explain binding of drug to HSA and globulins.
Describe salivary excretion as one of non-renal route of drug excretion with
suitable example.
Define non-linear pharmacokinetics and explain in brief causes of
Non-linearity.
Write a note on film theory as one of dissolution mechanism.
3. Solve any three (10×3=30)
What is mean by Pharmacokinetics model Classify and explain various
pharmacokinetic and pharmacodynamic parameters in detail.
Write a detailed note on one-compartment open model intravenous infusion.
Explain in detail various mechanism of drug absorption with suitable
examples.
Write detail various factors affected on renal excretion of drug.
Other Question Papers
Subjects
- anatomy, physiology and health education – i
- anatomy, physiology and health education – ii
- biochemistry
- biochemistry – i
- biochemistry – ii
- biopharmaceutics
- biotechnology
- clinical pharmacology
- herbal technology
- human anatomy and physiology – i
- human anatomy and physiology – ii
- medicinal chemistry – i
- medicinal chemistry – ii
- medicinal chemistry – iv
- microbiology
- modern dispensing and hospital pharmacy
- novel drug delivery systems
- organic chemistry – i
- organic chemistry – ii
- organic chemistry – iii
- pathophysiology (new cbcs)
- pathophysiology and clinical biochemistry – i
- pathophysiology and clinical biochemistry – ii
- pharmaceutical analysis – i
- pharmaceutical analysis – ii
- pharmaceutical analysis – iv
- pharmaceutical analysis – v
- pharmaceutical analysis – vi
- pharmaceutical busines management
- pharmaceutical engineering
- pharmaceutical enginering
- pharmaceutical inorganic chemistry
- pharmaceutical jurisprudence
- pharmaceutical microbiology
- pharmaceutical organic chemistry – ii
- pharmaceutical organic chemistry –i
- pharmaceutics – i (new cbcs)
- pharmaceutics – i (old-cbcs pattern)
- pharmaceutics – ii
- pharmaceutics – iii
- pharmaceutics – iv
- pharmacognosy – i
- pharmacognosy – ii
- pharmacognosy – iii
- pharmacology – i (new) (cbcs pattern)
- pharmacology – ii
- pharmacology – ii (cgpa pattern)
- pharmacology – iv
- physical pharmaceutics – i
- physical pharmacy – i
- physical pharmacy – ii
- sterile dosage forms