B.Pharm. (Semester IV) (New CBCS Pattern) Examination, 2018
pharmaceutical analysis ii
Day and Date Monday, 17-12-2018 Max. Marks 70
Time 2.30 p.m. to 5.30 p.m.
1. Multiple choice questions (1×15=15)
First proposed Oxygen flask combustion method.
Schoniger Peter Griessin
Karl Fischer None of these
For fluorine determination combustion is carried out glass
flask.
Silica glass Borosilicate
Soda glass Both and
Mordant black II is not used for determination of metals like
Ca Fe Zn Al
type of crucibles can be used for drying of precipitate upto
1000°c.
Silica Porcelein
Sintered glass None of above
Xylenol orange is not used in the estimation of
Zinc Thorium
Mercury Copper
0.75 gm of sodium nitrite in 100 ml gives M sodium nitrite.
0.1 0.05 0.01 1
gm of Zn+2 equivalent to 0.05 M C10H14N2Na2O8.
0.003269 0.006018
0.002639 None of above
P.T.O.
Seat
No. Set P
Set P
SLR-TV 27 *SLRTV27*
is unaffected by chemical reagents and heating prior to 500°c.
Munroe crucible Glass fibre discs
Permanent porous filter discs Gooch crucible
Erichrome black T shows clour at pH 6-7.
Red-Blue Violet-Red
Blue-Yellow Red-Yellow
10) For gaseous sampling °c temperatue required for silica
quartz tubes.
Above 500 Below 500
500 None of above
11) solvents are acidic in nature.
Aprotic Protogenic
Protophilic Amphiprotic
12) Paracetamol analysis involves limit test for
Chloride Sulphate
Heavey metal Arsenic
13) Primary aromatic amines formed type compound with nitrous
acid.
No reaction Stable
Unstable Phenol
14) The determination of halogen done by
Kjeldahl method
Karl-Fischer method
Oxygen flask combustion method
Argentometry method
15) RIA gives of the sample.
Radiating power Complex forming ability
Concentration None of these
Set P
*SLRTV27* SLR-TV 27
2. Answer any five
Define complexometric titration. How will you prepare and standardize 0.05 M
Disodium EDTA
Write the end point detection in sodium nitrite titration. Explain assay of
Sulphanilamide.
Write the Apparatus and procedure for Kjeldahl method.
Explain oxygen flask combustion method.
Define and classify ligand with suitable e.g. Explain assay Magnesium
sulphate powder.
Explain in detail ELISA technique.
3. Answer any three of the following (10×3=30)
Describe the classification of Non-aqueous titration. Write a note on assay
of Mebendazole and Salbutamol sulphate powder.
What is sampling Explain the sampling of liquid material.
Define Gravimetric analysis. Give in detail sampling, filteration and ignition.
Explain assay of Zinc sulphate by Gravimetry.
Write the theory, preparation and standardization of Karl-Fischer method.