THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[LN 343] OCTOBER 2018 Sub. Code: 2904
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH I PHARMACEUTICS
PAPER IV ADVANCES IN DRUG DELIVERY SYSTEM

Q.P. Code 262904
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. Explain the classification of polymers and applications of polymers in formulation
of controlled drug delivery systems.
2. Describe the design and development of dissolution, diffusion, PH and Ion
exchange controlled oral drug delivery system.
II. Write notes on: (10 x 6 60)
1. Protein binding of a drug influencing design and performance of SRDDS.
2. Activation-moduled controlled drug delivery system.
3. Long acting steroid preparation.
4. Permeation enhancers used in development of TDDS.
5. Preparation of Liposomes.
6. Advantages and disadvantages of muco adhesive drug delivery system.
7. Evaluation of ocular controlled drug delivery system.
8. Colon targeting.
9. Immunoconjugates.
10. Nanoparticles.