OCTOBER 2017 Sub. Code: 2904
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH I PHARMACEUTICS
PAPER IV ADVANCES IN DRUG DELIVERY SYSTEM

Q.P. Code 262904
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. Explain the characteristics of an ideal polymer to be used in CDDS? Discuss
biodegradable polymers commonly used in the preparations of Novel drug
delivery systems.
2. What are the advantages of targeted drug delivery systems? Discuss in detail about
liposomal formulations for drug targeting.
II. Write notes on: (10 x 6 60)
1. Influence of physico chemical properties in the development of sustained release
dosage forms.
2. Prodrug and solubilisation approach for bio-availability enhancement.
3. Insulin pump as CDDS module.
4. Role of Ion exchange resin in SR formulations.
5. In vitro evaluations of transdermal drug delivery systems.
6. Buccal drug delivery system.
7. Systemic absorption of drugs through nasal route.
8. Ocular inserts and its evaluations.
9. Particulate carriers.
10. Antibody based drug delivery system.