THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[LM 343] MAY 2018 Sub. Code: 2904
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH I PHARMACEUTICS
PAPER IV ADVANCES IN DRUG DELIVERY SYSTEM

Q.P. Code 262904
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. What is Microencapsulation? Mention different methods of Microencapsulation.
Describe any method in detail used for encapsulating a liquid drug to be converted
into a free flowing solid.
2. Give a detailed account of Parenteral controlled release drug delivery systems.
II. Write notes on: (10 x 6 60)
1. Potential advantages and disadvantages of Sustained release dosage forms.
2. Chemical approach for improvement of dissolution.
3. Biodegradable polymers.
4. Properties of drug to be considered in the design of Transdermal drug delivery
stystems.
5. Module for drug delivery in the GIT.
6. Muco adhesive drug delivery.
7. Design, mechanism and advantages of Ophthalmic inserts.
8. Why are liposomes considered versatile for parenteral targeted delivery?
9. Applications of resealed erythrocytes.
10. Magnetically responsive microspheres.