THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[LM 340] MAY 2018 Sub. Code: 2901
M.PHARM. DEGREE EXAMINATION
(Common to all Branches)
FIRST YEAR
PAPER I MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES
Q.P. Code 262901
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. Describe the different electronic transitions involved in UV spectrophotometry
with examples.
Discuss the principle and instrumentation of nuclear magnetic spectroscopy.
2. With neat labeled diagram, explain the principle and instrumentation of Gas
liquid Chromatography.
Explain the principle and instrumentation of spectrofluorimeter with a neat
diagram.
II. Write notes on: (10 x 6 60)
1. Write the theory and various types of ions produced in mass spectroscopy.
2. Describe the principle and instrumentation of DSC.
3. Discuss the principle and applications of flame emission spectroscopy.
4. Explain optical rotatory dispersion and circular dichroism with examples.
5. Write a note on degree of freedom, correlation and regression.
6. Explain the principle involved in supercritical fluid chromatography.
7. Discuss the fundamental vibrations of the molecules in IR spectrophotometry.
8. Write short notes on Radioimmunoassay.
9. Write a note on citation of references.
10. What is coupling constant? Briefly explain the various factors affecting the
coupling constant.