MAY 2017 Sub. Code: 2901
M.PHARM. DEGREE EXAMINATION
(Common to all Branches)
FIRST YEAR
PAPER I MODERN PHARMACEUTICAL ANALYTICAL TECHNIQUES
Q.P. Code 262901
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. Explain the principle and instrumentation of infrared spectrophotometer with a
neat diagram.
Discuss the various techniques employed in the assay of multicomponent
mixture by UV spectrophotometer.
2. What is electrophoresis? Explain the principle, instrumentation and
applications of Gel electrophoresis.
Describe the theory, instrumentation and applications of DTA.
II. Write notes on: (10 x 6 60)
1. Discuss the theory involved in fluorescence with the help of Jablonski diagram.
2. With a neat diagram explain the construction and working of Hollow cathode lamp
and Photomultiplier tube.
3. Explain normal phase, reverse phase and two dimensional chromatography.
4. Write short notes on Quenching.
5. Write short notes on Chi-square test and student test.
6. Write a note on the theoretical aspects of NMR and ESR.
7. Explain the various development techniques and applications of paper
chromatography.
8. How X-rays are generated? Briefly explain X-ray powder diffraction method.
9. Write an account on detectors used in HPLC.
10.Describe the principle involved in mass spectroscopy.