M.Sc. DEGREE EXAMINATION, APRIL 2016
Second Semester
Biotechnology
IMMUNOBIOLOGY
(CBCS 2013 onwards)
Time 3 Hours Maximum 75 Marks
Part A (10 2 20)
Answer all questions.
All questions carry equal marks.
1. Define CTL.
2. What is ADCC?
3. Erythropoietin.
4. Define allotype.
5. IgM.
6. What is meant by exogenous antigens?
7. Rheumatoid factors.
8. What is meant by histocompatible?
9. Define accelerated rejection.
10. Atopy.
Sub. Code
501201
RW-10858
2
Wk 4
Part B 5 25)
Answer all questions choosing either or
11. Give an account on Secondary lymphoid organs.
Or
Write down difference between specific and non
specific immunity.
12. Define immunogenicity and briefly describe the
properties of immunogens.
Or
Write about structure and biological functions of
antibodies.
13. Describe the role of antigen presenting cells.
Or
Given an account on clinical applications of
monoclonal antibodies.
14. Draw the cascade of Lectin pathway of complement
activation with suitable diagram.
Or
Name five autoimmune disorders.
15. Explain about the various types of rejections with
suitable examples.
Or
Define Acquired Immunodeficiency Syndrome
(AIDS) and explain the pathogenesis of HIV-1.
RW-10858
3
Wk 4
Part C 10 30)
Answer any three questions.
16. Describe in detail about T cell maturation and
differentiation with neat sketch.
17. Give an account on the structure, properties and
functions of various immunoglobulins.
18. Write a brief account on components of complement
system.
19. Define delayed type I hypersensitivity and explain
different methods used for the detection of type I
hypersensitivity.
20. Give a detailed account on edible vaccines.