M.Sc. DEGREE EXAMINATION, APRIL 2017
Second Semester
Zoology
IMMUNOLOGY AND IMMUNOTECHNOLOGY
(2016 onwards)
Time 3 Hours Maximum 75 Marks
Part A (10 x 2 20)
Define/explain all of the following.
All questions carry equal marks.
1. Melanin.
2. Bursa of Fabricius.
3. Cognate antigen.
4. Interferons.
5. Cytokines.
6. T-helper cells.
7. Toll-like receptor.
8. Vaccines.
9. Autoimmune disease.
10. SCID.
Sub. Code
509201
RW-197
2
Sp4
Part B x 5 25)
Answer all questions choosing either or
11. Explain the functional significance of intermediate
defense system.
Or
Distinguish between primary and secondary
lymphoid tissues/ organs with examples.
12. Explain antigen presenting cells with suitable
examples.
Or
What are T cells? Explain the subpopulation of T
cells.
13. Draw and describe the general structure of
immunoglobulin.
Or
What is immunodeficiency? Draw and explain the
structure of HIV-1.
14. Define hypersensitivity. What is the role of type I
hypersensitivity on immune' complex clearance?
Or
What is immunotherapy? Give some examples of
immunotherapeutic agents.
15. Give a brief account on principle and applications of
western blot.
Or
Describe briefly the principle and applications of
flowcytometry.
RW-197
3
Sp4
Part C x 10 30)
Answer any three questions.
All questions carry equal marks.
16. Give a detailed account on functional differentiation of
T-lymphocytes.
17. What are antigen presenting cells? Explain the
mechanism of antigen presentation by endocytic
pathway.
18. Describe the structure and functions of BCR.
19. What is immunoprophylexis? Explain preparation and
efficacy of any two types of vaccines.
20. Write notes on
ELISA
Hybridoma technology.