FACULTY OF PHARMACY
B. Pharmacy 4/4 I Semester (Main) Examination, November 2016
Subject: Dosage Formulations Design (Pharmaceutics III)
Time: 3 Hours Max.Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Write about various physical properties of active pharmaceutical ingredient
(Bulk drug) in preformulation study. 14
OR
Enumerate the various causes of decomposition of medicinal agents. Discuss the
stabilization of drug formulation against oxidation and hydrolysis. 14
2 Explain rationale behind the Sustained Release Drug Formulations (SRDF). Discuss
the various techniques for making SRDF? How are they evaluated? 14
OR
Write the importance of microencapsulation in pharmacy. Write in detail about air
suspension technique and solvent evaporation. 14
3 Write concept of liposomal Drug Delivery Systems (DDS). 7
Write preparation and characterization of nanoparticles. 7
OR
Discuss about ocuserts. 7
Explain the evaluation methods of Transdermal Drug Delivery Systems. 7
4 Define bioquailability and bioequivalence. Describe in detail bioequivalence
procedure. 7
What are the different methods of measuring bioquailability? 7
OR
Write a note on types of validation. 7
Write the importance of validation and CGMP in production of pharmaceutical
products. 7
5 Write briefly on master formula record and batch production record. 7
Explain briefly about auditing. 7
OR
Discuss about various control parameters during production of tablets. 14