FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutics) II-Semester (Main) Examination, August 2018
Subject: Computer Aided Drug Delivery System
Time: 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 Write short note on "Statistical Modeling". 3x5
Descriptive versus mechanistic modeling.
Population modeling
2 Write about ICH Q8 guide lines. What are the regulatory and industrial views on
quality by design? 15
3 Write about active transport and explain any three of the following 3x5
h PEPTI
ASBT
OCT
OATP
BBB choline transporter
4 How to screen various parameters in pharmaceutical product development by
using computers? 7 ½
What do you mean by factorial designs in optimization technology? 7 ½
5 Discuss in detail about computer simulation in pharmacokinetic and
pharmacodynamic studies. 15
6 Write short notes on clinical data collection. Give detail description about the
process before, during and after data collection. 15
7 Explain various applications of artificial intelligence. 7 ½
Write notes on pharmaceutical automation. 7 ½
8 What do you mean by "Biowavier consideration" and where do you apply
these biowavier studies? 7 ½
Write detail notes on Invitro, Invivo correlation. 7 ½