FACULTY OF PHARMACY
M. Pharmacy (Pharmaceutics) II-Semester (Main) Examination, August 2018
Subject: Molecular Pharmaceutics
(Nano Technology and Targeted Drug Delivery Systems)
Time: 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 Explain the concepts, events and biological processes involved in drug
targeting.
Explain in detail about targeting of drugs to tumor cells.
2. Explain the methods of preparation and evaluation of nanoparticles.
3 Explain the methods of preparation and evaluation of microspheres.
Explain the methods of preparation of aquasomes.
4 Write about containers, propellants and evaluation tests for pharmaceutical
aerosols.
Explain about intranasal drug delivery system.
5 Explain about bone marrow transplantation in exvivo gene therapy.
Give a brief note on invivo gene therapy
6 Discuss in detail gene expression systems (both viral and nonviral gene
transfer).
Give an account of liposomal gene delivery system.
7. Give a brief account of aptamers; ii) Therapeutic antisense molecules.
8. Explain the methods of preparation and evaluation of liposomes.