FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PHARMACOLOGY
PAPER II
PHARM/D/16/34/II
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Mention the various classes of anti-depressant drugs along with
examples for each class.
Enumerate the mechanism(s) of actions, uses and side effects of
TCAs.

2. Pharmacotherapy of MDR XDR tuberculosis.
Adverse effects, precautions and important drug interactions of
rifampicin.
5+5
3. Principle, applications and limitations of:
HPLC
ELISA
5+5
4. Enumerate dual PPAR agonists.
Mechanisms of action, advantages and therapeutic potential of
dual PPAR agonists.

5. Enumerate the different preparations and advantages of newer
insulins.
Role of incretin based therapy for diabetes mellitus.
5+5
6. Uses and side effects of chloroquine.
Pharmacotherapy of chloroquine resistant malaria.

7. Mechanism of action, uses and side effects of NSAIDs.
Enumerate DMARDs used in rheumatoid arthritis.

8. Classify drugs used in the treatment of bronchial asthma.
Advantages, precautions and side effects of inhalational therapy
in bronchial asthma.

9. Pharmacotherapy of CHF.
Role of Angiotensin Receptor Neprilysin Inhibitor (ARNI) in CHF.
5+5
10. Mechanism of action and uses of corticosteroids.
Side effects of long term corticosteroid therapy.