FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PHARMACOLOGY
PAPER-II
PHARMA/D/17/34/II
Time: 3 hours
Max. Marks: 100
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space
• Answer all the parts of a single question together.
• Start the question to a question on a fresh page or leave adequate space between two
answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Mention various oral anti-diabetic agents, giving
examples.
Mechanism of action, uses and adverse effects of
DPP-4 inhibitors.
5+5
2. Mention different class of anti-platelet agents giving
examples.
Briefly mention mechanism of action of ADP receptor
antagonist.
5+5
3. Enumerate drugs causing nephrotoxicity and
mention measures to clinically monitor the patient on
nephrotoxic drug.
What role Pharmacogenomics can have in drug
discovery?
5+5
4. Enumerate giving reasons of life saving and life style
drugs giving examples.
What is the pharmacological rationale and dosage
schedule of adrenaline in anaphylactic shock?
5+5
5. Enumerate non volatile general anaesthetic agents.
Etomidate is preferred inducing agent in elderly
patients. Justify
Compare propofol and ketamine.

6. Outline pharmacotherapy of peptic ulcer.
Enumerate the different preparations and therapeutic
uses of prostaglandins as oxytocics.
5+5
FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
7. Mechanism of action and uses of interferons.
Give critical appraisal of therapeutic uses, dosage
schedule and adverse reaction of oseltamivir.
5+5
8. Mention principles and applications of HPLC.
Current approaches of pharmacotherapy of cardiac
failure
5+5
9. Pharmacotherapy of chronic bronchial asthma
Enumerate drugs acting on dopamine receptors with
therapeutic uses
.
5+5
10. Pharmacological basis of use and adverse effects of
alpha-adrenoceptor antagonists
Therapeutic status and adverse reactions of lithium
carbonate
5+5