FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2016
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
MICROBIOLOGY
PAPER IV
MICRO/D/16/18/IV
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Principle and applications of MALDI-TOF in clinical
microbiology.
4+6=10
2. Point of care tests.
10
3. Principle and applications of reverse vaccinology.
6+4
4. Define vaccine derived polio virus and the current strategies in
global polio vaccination programme.
2+8
5. Next generation sequencing.
10
6. Enumerate mechanisms of Linezolid resistance and its
laboratory detection.
6+4
7. Define quasi species and their role in disease.
4+6
8. Define biosensors and its application in Microbiology.
2+8
9. New guidelines of Biomedical Waste Management Rules,
2016.
10
10. Application of stem cell research in Microbiology.
10