FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
ENDOCRINOLOGY
PAPER I

POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
ENDO/D/17/07/I
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two
answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Describe the steps in expression of a protein encoding
gene and subcellular structure of cells that secrete protein
hormones.
5+5
2. Various assays for hormone assessment.
10
3. What are confidence intervals, power and type I II error
probability?

4. Adipose tissue as an endocrine organ.
10
5. Disposition index and its relation to insulin resistance. 5+5
6. Endocrine maternal adaptation to pregnancy.
10
7. 46 ,XY disorders of sex development.
10
8. Monogenic causes of obesity and obesity syndromes due
to chromosomal re-arrangements.
5+5
9. Quality control systems and investigation of discordant test
values.
5+5
10. Assessment of β cell reserve. 10