B.Pharmacy (Semester IV) (CGPA) Examination, 2017
PATHOPHYSIOLOGY AND CLINICAL BIOCHEMISTRY II
Day and Date Wednesday, 17-5-2017 Total Marks 70
Time: 3.00 p.m. to 6.00 p.m.
Instructions • Figures to right indicate appropriate marks.
• Appropriate Flow Charts, Algorithms and Illustrations shall
fetch appropriate marks.
1. Choose most appropriate alternative for following Multiple Choice Questions
(15×1=15)
Systemic Venous Congestion and Peripheral Edema are features of
type of heart failure.
Right Sided Backward
Left Sided Forward
The pathologic form of Monocytes upon imbibition of Oxidized LDL within the
Intima is
Langerhan's Cells Giant Cells
Adipose Cells Foam Cells
Ischemic Heart Disease is associated with Coronary Atherosclerosis of major
coronary arteries with more than of luminal narrowing.
45 55
65 75
Emphysema occurs due to deficiency of anti-elastase called
Aminopeptidase αl -Trypsin
αl -Antitrypsin Fibrinolysin
Pathologic Legions found in Neurodegenerative Diseases like Parkinson's
Disease are
Nissl Bodies Lewy Bodies
Ketone Bodies Golgi Bodies
Jerking movements of entire body are observed in phase of
Generalized Seizures.
Tonic Clonic
Post-ictal All of these
is a complication of Pneumonia.
Renal Failure Ascites
Empyema Stroke
The Glycoprotein responsible for attachment of HIV with the CD4 Cells
is
gp120 gp41
gp53 gp21
Vertical Transmission of HIV is
Transmission of HIV from an infected partner through an unprotected
sexual intercourse
Transmission of HIV from an infected mother to her foetus
Transmission of HIV through transfusion of blood from an infected donor
Transmission of HIV through use of contaminated unsterilized needles
in drug abusers
10) Antibodies mediating anaphylatic reactions are type.
IgM IgG IgA IgE
11) Accumulation of edematous inflammatory fluid within the synovium in RA is
called
Osteophyte Pannus Formation
Crepitus Podagra
12) The Laboratory tests useful in diagnosis of Myasthenia Gravis are
and
Forward Arm Abduction Time and Tensilon Test
X-Ray and Endoscopy
Biopsy and EEG
CBC and Urine Culture
13) A complication of Type-2 Diabetes in elderly patients with acute severe
infections with plasma glucose levels above 500 mg/dl is
Non-Ketotic Hyperosmolar Coma
Diabetic Ketoacidosis
Diabetic Nephropathy
Diabetic Neuropathy
14) TSH levels are in Hypothyroidism.
Normal Elevated
Decreased Absent
15) Determination of serum bilirubin is a
Renal Function Test Thyroid Function Test
Neurological Test Liver Function Test
2. Answer the following (any five)
Define Shock. Describe Types of Shock.
Write definition, causes and pathogenesis of Emphysema.
Summarize the pathogenesis and manifestations of Parkinson's Disease.
Write briefly about Diagnostic and Analytical Applications of Enzymes.
What are Hypersensitivity Reactions Mention their types. Explain Type-I
Hypersensitivity Reactions.
Define Hyperthyroidism. Mention its causes, signs and symptoms.
SLR-D 20
3. Answer the following (any three) (3×10=30)
What is Congestive Heart Failure Describe causes, Pathogenesis and Clinical
Manifestations of CHF.
Write definition and enlist types of Pneumonia. Write an account on stages of
bacterial lobar pneumonia.
Write the meaning of 'Seizure' 'Convulsion' and 'Epilepsy'. Enumerate types of
seizure. Write Pathogenesis of Epilepsy.
Define Hyperglycemia and Diabetes Mellitus. Write clinical features of Diabetes
Mellitus. Write Pathogenesis of type-1 and type-2 Diabetes Mellitus.