B.Pharmacy (Semester
IV) (NEW CBCS) Examination, 2018
Pathophysiology and Clinical Biochemistry II
Day and Date Wednesday, 16-5-2018 Max. Marks 70
Time 3.00 p.m. to 6.00 p.m.
Instructions Mention appropriate question numbers and sub-question numbers.
Figures to right indicate full marks.
Use of appropriate and exemplary algorithms, flow charts or illustrations should be assessed similar to descriptive answers.
1. Choose an appropriate alternative for following multiple choice questions (1×15=15)
Inhomogeneity in ERP of Atrial fibers under excessive vagus nerve influence leads to
Ectopic Pacemaker Activity
Reentry
Fractionation of impulse
After Depolarizations
is the most common cause of Ischemic Heart Disease.
Coronary Atherosclerosis Renal Insufficiency
Systemic Infections Malnutrition
Elevated and reduced is the major risk factor for coronary atherosclerosis.
HDL Cholesterol and LDL cholesterol
Triglycerides and HDL Cholesterol
VLDL Cholesterol and LDL Cholesterol
LDL Cholesterol and HDL Cholesterol
A myocardial infarction which involves entire thickness of myocardium is called
Laminar Infarct Microinfarct
Transmural Infarct Marginal Infarct
P.T.O.
Set
P
Set P
Substernal chest pain occurring at rest and relieved by sublingual nitroglycerine tablet is called
Variant Angina
Crescendo Angina
Unstable Angina
Classical Angina
Persistent cough with expectoration on most days for 2-3 months in a year lasting for 2 or more consecutive years is called
Asthma Emphysema
Chronic Bronc hitis Asthma
is a cause and predisposing risk factor for Pulmonary Embolism.
Deep Vein Thrombosis Vitamin K Deficiency
Head Injury Liver Disease
Deficiency of leads to emphysema.
Elastase Alpha-1-Antitrypsin
Anti-elastase Lecithin
Beta amyloid protein aggregates are found in brains of patients with
Alzheimer's Disease Epilepsy
Parkinson's Disease Schizophrenia
10) Brief tonic phase, clonic jerky contractions, unconsciousness and amnesia occur in
Grand Mal Epilepsy Petit Mal Epilepsy
Temporal Lobe Epilepsy Juvenile Seizures
11) Most of the Macro and Microvascular complications of type 2 Diabetes occur due to a metabolite of glucose called.
Insulin Sorbitol
Glucagon Fructose
12) CD4 T Cell counts of lead to serious deficiency of immune system function in AIDS.
600-1000/cu mm 1000/cu mm
1000/cu mm 350/cu mm
13) An IgE mediated hypersensitivity reaction with manifestations ranging from simple rashes to anaphylaxis is called type hypersensitivity reaction.
Immediate Cytolytic
Arthus Delayed
SLR-TA 29 *SLRTA29*
Set P
*SLRTA29* SLR-TA 29
14) Adulthood hypothyroidism with non-pitting edema and cold intolerance is
Cretinism Thyrotoxicosis
Myxoedema Grave's Disease
15) Determination of Serum Creatinine is a
Kidney Function Test
Liver Function Test
Cardiac Function Test
Thyroid Function Test
2. Answer any five of the following
Define Angina Pectoris. Explain types of Angina Pectoris in detail.
What is Pulmonary Embolism Describe etiopathogenesis and manifestations of pulmonary embolism.
What is Parkinson's Disease Mention Signs and symptoms. Add a note on etiopathogenesis of Parkinson's disease.
Enlist Liver function tests. Describe serum Bilirubin estimation with its clinical significance.
Differentiate between Type 1 and Type 2 diabetes mellitus.
Write causes and manifestations of hypothyroidism.
3. Answer any three of the following (3×10=30)
Define epilepsy. Briefly explain types of seizures. Write etiopathogenesis of epilepsy.
Summarize causes, pathogenesis and manifestations of Rheumatoid arthritis.
Define shock. Brief out its types. Explain stages of shock.
Write an account on of causes, triggers, pathogenesis and manifestations of Bronchial Asthma.