B.Pharmacy (Semester III) (CGPA) Examination, 2017
PHARMACEUTICAL ANALYSIS I
Day and Date Saturday, 13-5-2017 Total Marks 70
Time 3.00 p.m. to 6.00 p.m.
1. Multiple Choice Questions (15×1=15)
method is superior method than gravimetric method.
Instrumental method Gasometric method
Microbiological method Volumetric method
Electrical conductance is measured by Instrumental method.
Polarography Conductometry
Potentiometry Thermal method
The no. of formula weight of solute contained in ml of solution.
1 ml 1000 ml 10 ml 100 ml
The law of mass action was first proposed by
Goldberg and Wage Mohr
W. Ostwald None of these
Phenol red has PH range
6.8 to 8.4 3.1 to 4.4
8.3 to 10.5 11.1 to 12.7
In titration of weak base with strong acid indicator is commonly
used.
Phenolphthalein Thymol blue
Methyl red Thymolphthalein
4 gm of NaOH dissolved in 1 lit. of distilled water M.
1 M 0.5 M 0.1 M 0.05 M
Assay of Ephedrine hydrochloride is type of titration.
Acid-base Titration
Non-aqueous acid-base Titration
Precipitation Titration
Redox Titration
Loss of electrons from any species
Oxidation Reduction
Oxidising agent Reducing agent
10) indicator have different colour in their oxidized form and
reduced form.
Internal Self
External None of these
11) Each ml of 0.05 M Iodine solution is equivalent to gm of
sodium thiosulphate.
0.02482 0.04282
0.08224 0.02842
12) Combination of ionic species to form a very insoluble product.
3 2 4 None of these
13) Each ml of 0.1 M AgNO3 is equivalent to gm of sodium chloride.
0.00585 0.00855
0.004346 0.003429
14) Degree of reproducibility of series of measurements on the same property

Precision Accuracy
Relative error Absolute error
15) The error arises from imperfection in measuring device
Instrumental Operational
Method Proportional
16) The error arise from incorrect sampling and incomplete reactions involved in
determination
Method error Personal error
Indeterminate error Reagent error
2. Answer any five
Define Primary standard and secondary standard. Write a note on different
chemical method.
Write a note on Instrumental and Microbiological method of Analytical
techniques.
What is law of mass action Write a note on mixed indicator and Universal
indicator.
Give the assay of ferrous sulphate powder I.P. Write a note on external
indicator.
Write preparation and standardisation of 0.1 M silver nitrate. Explain Adsorption
Indicator method.
Define Error, Accuracy, Precision. Explain how error can be minimised.
3. Answer any three of the followings (3×10=30)
Write the difference between the Mohr's method and Volhard's method. Explain
assay of sodium chloride injection by Volhard's method.
Define Redox titration. Explain chromophore method of Indicator.
Define Neutralisation titration. Explain neutralization curve of weak base and
strong acid. Write the assay of Ephedrine hydrochloride powder I.P.
Write the difference between Iodimetric and iodometric titration. Explain assay
of sodium thiosulphate powder.