B.Pharmacy (Semester III) (CGPA) Examination, 2017
ORGANIC CHEMISTRY II
Day and Date Tuesday, 9-5-2017 Total Marks 70
Time 3.00 p.m. to 6.00 p.m.
Multiple Choice Questions
I. Choose the most appropriate one from the following answers (15×1=15)
Nucleophilic substitution of-Cl is possible by
OR
NH2 All
The chief factor that makes nucleophilic substitution easier on a carbonyl
carbon than an alkane carbon is
Steric bulk Electronic factors
Flatness and facile bond angle None
Less basic amine of the following is
CH3 Ar NH2 Ar NH2
NO2 Ar NH2 R NH2
Correct name of the compound CH3 CH CH (C2H5) C OH
is
2 OH 3 ethyl butanoate 2 ethyl 3 OH butanoate
3 Carboxy 4 OH pentane None
Imines are obtained when are reacted with an amine.
Aldehydes Ketones
Both Neither
Tollen's reagent can be used to distinguish
Aldehydes and higher ketones Aldehydes and lower ketones
Aldehydes and ketones Neither
Identify the five membered heterocycle with two hetero atoms from the list
below
Indole Pyrrole
Pyrazole Diazine
Unique reaction of naphthalene and anthracene is
Electrophilic aromatic substitution Nucleophilic aromatic substitution
Electrophilic addition Oxidation
Product obtained on heating phthalic acid in presence of ammonia is
Maleimide Phthalimide
Phthalic anhydride None
10) An amine on treating with excess of an alkyl halide yields
Alkyl amine Tetraalkyl amine
Trialkyl amine Dialkyl amine
11) rule helps us to differentiate between benzene and
non-benzene like molecules.
Hund's rule Frie's rule
Huckel's rule Woodward's rule
12) A reaction that requires at least one non α -hydrogen containing carbonyl
compound is reaction.
Mannich Reformatsky
Perkin Cannizzaro
13) Identify a compound which is anti-aromatic from the following
Cycloheptatrienyl anion Cyclobutadiene
Cyclopentadienyl cation Cyclooctatetraene
14) reduction reaction employs the following reagents NaNH3,
EtOH.
Wolff-Kishner Clemmensen
Birch Catalytic
15) Oxidation of phenanthrene with ozone yields
Diphenyl dicarboxyl Diphenyl dicarboxaldehyde
10-diphenanthrone None
II. Answer any five questions of the following.
How are Thiophene and Isoquinoline prepared Explain.
Explain the terms 'reactivity' and 'orientation' in case of reactions of Benzene.
Describe the role of electron withdrawing and electron donating groups on
'reactivity' and 'orientation'.
How do you separate a given mixture of amines into primary, secondary and
tertiary amines using Hinsberg's method Explain with an example.
Compare reactions for pyrrole with indole.
Describe how alcohols, amines and Grignard's reagent and R-Li behave with
aldehydes.
Write the laboratory methods available for preparing Anthracene.
III. Answer any three questions of the following (3×10=30)
Explain the reaction, mechanism, conditions of reaction, applications and
limitations of
Cannizzaro.
Perkin reaction.
Write the methods of preparation and chemical reactions of isoquinoline.
Write five important reactions of phenols and amines.
Write briefly about
Explain Oppennauer oxidation and Reformatsky reactions.
Huckel's rule and Benzene structure.