M.Sc. DEGREE EXAMINATION, APRIL 2017
Seocnd Semester
Bioinformatics
Elective II — IMMUNOLOGY AND
IMMUNOTECHNOLOGY
(2016 onwards)
Time 3 Hours Maximum 75 Marks
Part A (10 x 2 20)
Answer all questions.
All questions carry equal marks.
1. State the functions of thymus.
2. Define epitope.
3. What is the difference between NK cells and APC?
4. What is humoral immunity?
5. Name any two attenuated vaccines.
6. What are autoimmune disorders?
7. Name the cells involved in type III hypersensitivity.
8. What is MHC?
9. Define immunoprecipitation.
10. Write the applications of western blot.
Sub. Code
502502
RW-190
2
Wk ser
Part B 5 25)
Answer all questions.
11. Draw the structure of primary lymphoid organs.
Or
Write about complement system.
12. Explain the functions of T-cells and B-cells.
Or
Explain about cell mediated immunity.
13. Describe active and passive immunity.
Or
Explain the mechanism of infection and immune
response.
14. Write a note on immuno therapy mediated cancer
treatment.
Or
Discuss about Graves disease and multiple
sclerosis.
15. Explain RIA.
Or
What is hybridoma technology? Write its
applications.
Part C 10 30)
Answer any three questions.
16. Elucidate different types of antibodies and their
functions.
17. What is hematopoiesis? Explain in detail.
RW-190
3
Wk ser
18. Describe the classification of vaccines and its role in
disease prevention.
19. Explain the types of hypersensitivity reactions.
20. Write about the mode of occurrence of AIDS, its diagnosis
and treatment.