B.Pharm. I(Semester II) (New CBCS) Examination, 2018
Pharmaceutical ORGANIC CHEMISTRY I
Day and Date Monday, 7-5-2018 Max. Marks 75
Time 10.30 a.m. to 1.30 p.m.
1. Multiple Choice Questions. (20×1=20)
SN1 reaction occurs through the intermediate formation of
carbanion carbocations
free radicals none of these
Lucas reagent is
HCl/Zncl2 HNO3/Zncl2 Pd/Baso4 NH4
Benzaldehyde reacts with mixture of conc.H2SO4 and HNO3 gives
P-nitro benzaldehyde O-nitro benzaldehyde
P-nitro benzoic acid M-nitro benzaldehyde
When benzyne reacts with 3-butadiene is called as
Diel's-alder reaction Elimination
Substitution None
Oxidation of secondary alcohol gives
ketones amines aldehydes none
A method to obtain primary amine directly from amides is
Fries Hoffman Claisen None
In victor meyer test primary alcohol produces colour.
Blue Red blood Green None
The carbon atoms in an alkene are
SP4 hybridized SP3 hybridized
SP hybridized SP2 hybridized
Imines are obtained when are reacted with an amine.
Aldehyde K Ketone Both None
10) An amine on treating with excess of an alkyl halide yields.
an alkyl amine tetra alkyl amine
trialkyl amine dialkyl amine
11) In cannizarro's reaction product obtained is
only carboxylic acid
only alcohol
mixture of carboxylic acid and alcohol
none
12) Reverse reaction of MPV reduction is
oppenaur oxidation aldol condensation
mannich reaction perkin reaction
13) Which of the following compound will not be easily oxidised
primary alcohol secondary alcohol
tertiary alcohol aldehyde
14) Pyrolysis of alkanes is carried out at °C.
0 200 200 400 500 700 900 1000
15) If the double bonds are separated by one single bond then the diene is called
isolated conjugated
non-conjugated none
16) Lindlar's catalyst is
LiAIH4 Pd/Baso4 in quinoline
NH2NH2 HCl/Zncl2
17) Alkyl halides undergoes
substitution elimination
addition both and
18) The isomers of a substance must have
same chemical properties same molecular weight
same structural formula same functional group
19) The reaction of a sodium alkoxide with an alkyl halide is called
Wurtz fitting Williamson's synthesis
Perkin reaction Aldol condensation
20) Methane is produced by hydrolysis of
Al4C3 Dry ice
2-butane CaC2
2. Answer any seven of the following.
What are the laboratory methods of preparation of alkenes
ii) Define and classify structural isomers with suitable example.
iii) Write any five chemical reactions of aliphatic amines.
iv) Write a note on 2 and 4 addition reactions of 3-butadiene.
How will you prepare alkyl halides
vi) Write methods of preparation of alkanes.
vii) Write a note on nucleophilic addition reactions of aldehydes and ketones.
viii) Write any five chemical reactions of carboxylic acids.
ix) Write structures of compounds from given IUPAC names.
4-dimethyl-1-pentene
ii) 2-Bromo-1-chloro-4-methyl pentane
iii) 4-hexadien-1-01
iv) 3-Buten-2-one
4-dimethylhexanoic acid.
3. Solve any two. (10×2=20)
Write in detail mechanism, stereo chemistry of nucleophilic substitution reactions of alkyl halides unimolecular and biomolecular.
ii) Write methods of preparation and chemical reactions of alcohols.
iii) Write in detail reaction, mechanism, conditions,criterias and applications of
Aldol condensation
ii) Perkin condensation.