B.Pharmacy (Semester II) (New CBCS) Examination, 2018
pharmaceutical organic chemistry I
Day and Date Monday, 10-12-2018 Max. Marks :75
Time 2.30 p.m. to 5.30 p.m.
1. Multiple Choice Questions 20
Victor meyers test is not given by
(CH3)3 COH C2 H5 OH
(CH3)2 HCOH CH3 CH2 CH2 OH
In Diels alder reaction the 3 butadiene is reacted with
100°C to form Tetrahydro benzaldehyde.
Acroline Aniline Acytyline Salicylate
Propadiene CH2 C CH2 is
Cumulated diene Conjugated diene
Isolated diene None of above
Isobutyl group is which type of an alkyl group
Primary Secondary Tertiary None
According to anti Markovnikov's rule when propylene reacts with HBr in
presence of peroxide product is
n propyl bromide Isopropyl bromide
Butyl bromide Isobutyl bromide
Which of the following compound would react most rapidly in an SN2
reaction
CH3 CH2 I CH2 CHI
(CH3)2 CHI (CH3)3 Cl
2 dibromo ethane is formed by the reaction between
CH2 CH2 and Br2
Acetylene with excess of HBr
Ethylene with excess of HBr
2 dichloro ethane with Br2
P.T.O.
Set P
SLR-TV 6 *SLRTV6*
What is the IUPAC name of given structure CH3 CH CH CH2 OH
2 buten 1 01 2 buten 4 01
2 buten 2 01 2 butan 4 01
Less basic amine of the following
CH3 Ar NH2 Ar NH2
NO2 Ar NH2 R NH2
10) Tollen's reagent can be used to distinguish
Aldehydes and higher ketones Aldehydes and lower ketones
Aldehydes and Ketones Neither
11) 2-bromo butane reacts with alcoholic KOH to give
1 butene 2 butene 1 butenol 2 butane
12) Alcohols reacts with PCl5 to give
Alkene Alkyl halide Acid None of these
13) Cross cannizzaro's reaction is given by
C6H5 CHO, HCHO C6H5 CHO, CH3CHO
CH3 CHO, HCHO All of above
14) Which of the following is strongest acid
Water Formic Acid
Acetic acid Propanoic acid
15) In Hofmann's method for separation of 2° and 3° amines, the reagent
used is
acetyl chloride diethyl oxalate
nitrous acid none of above
16) Which of the diazonium salt is most stable
aryl diazonium salt alkyl diazonium salt
cyclo alkyl diazonium salt None of above
17) Primary alcohol is obtained by
Hydration of alkene dehydration of alkenes
Dehydrogenation of alkenes None of above
18) Benzylamine reacts with nitrous acid to form
Azo benzene Benzyl alcohol
Benzene Phenol
Set P
*SLRTV6* SLR-TV 6
19) Alkyl halides almost insoluble in water because
They have low polarity
They are covalent compound
They do not form hydrogen bond with water
None of above
20) SN1 mechanism proceeds intermediate state.
Free radical Carbonium ion
Pentavalent transition Carbanion state
2. Answer any seven of the following
Write any five chemical reactions of aliphatic amines.
ii) Write methods of preparation of alcohols.
iii) Explain any five chemical reactions of alkenes.
iv) Write methods of preparation of butadiene.
Write chemical reactions of alkanes.
vi) Explain any four methods of preparation of carboxylic acids and explain
effect of substituent on acidity.
vii) Write methods of preparations of aldehydes and ketones.
viii) Write a note on SN1 and SN2 reactions of Alkyl halides.
ix) Draw the structures from given IUPAC names or common names
2 oxo 3 methyl pentane
ii) 2 methyl 2 phenyl heptanol
iii) 5 hydroxy hexanoic acid
iv) 2 butanoic acid
Isobutyl alcohol.
3. Solve any two (10×2=20)
Write mechanism, reaction, conditions and criteria along with applications
of following
Cannizzarro's reaction
ii) Benzoin reaction.
How will you separate a mixture primary, secondary and tertiary alcohols.
Explain in detail E1 and E2 reaction.