B.Pharmacy (Semester VI) (CGPA) Examination, 2018
clinical pharmacology
Day and Date Thursday, 20-12-2018 Total Marks 70
Time 2.30 p.m. to 5.30 p.m.
1. Multiple choice questions (15×1=15)
Clinical pharmacology deals with all aspects of the study of
drugs in man.
Scientific Non-scientific
General Animal
Drugs with half-lives are more likely to require loading doses
for acute treatment.
Short Longer
Intermediate Very shorter
Biomedical research involving human subjects, the guidelines having
basic ethical principle.
Respect for person Beneficene
Justice All of above
term is usually reserved for seriously harmful effects of large
doses of a drug.
Toxic effect Side effect
Adverse drug reaction Intolerance
Alterations due to advanced age including changes in
Drug-protein binding Drug metabolism
Drug distribution All of the above
Case studies in the health sciences provide
Personal history of an individual patient
Information about one or more health problems
Both and
Other than and
P.T.O.
Set P Seat
No.
Set P
SLR-TV 42 *SLRTV42*
A neonate is less than days of age.
8 18
28 365
A pioneer clinical pharmacologist
Prof U. K. Sheth Harry Gold
Clinicians Other than and
Patient with renal impairment have altered
Pharmacokinetic profile Renal clearance and elimination
Elimination half life All of above
10) trials are aimed to see that whether the new drug have a use
full therapeutic activity or not.
Preclinical Clinical
Treatment Diagnostic
11) trial is more valid if carried out in double blind controlled manner.
Phase-I Phase-II
Phase-IV None
12) Auto allergy is the type of hypersensitivity.
Type-I Type-II
Type-III Type-IV
13) is an important cause of absorption interactions.
Intra luminal binding G. I. Motility
Mucosa damage All of the above
14) The neonatal liver has less capacity for
Oxidation Conjugation
Glucuronidation All of the above
15) Knowledge of the pharmacological basis of drug interactions is essential
in prescribing a drug to obtain a interaction.
Desirable Recognizing unwanted
Preventing unwanted All of the above
Set P
*SLRTV42* SLR-TV 42
2. Answer any five of the following questions
Define clinical pharmacology and give the objectives of clinical pharmacology.
Give the scope and general applications of clinical pharmacokinetics.
Explain ethics of research.
Write a note on sources of adverse drug reactions in response to drug.
Short note on pharmacokinetic drug interactions.
What is Geriatric pharmacology Extend the problems of
pharmacokinetic aspects of drug with suitable example.
3. Answer any three of the following (10×3=30)
Discuss in detail complications of withdrawl of drug therapy. Add note on
dosing of drugs in renal failure.
Describe pharmacoepidemiology with different types of observational studies.
What is asthma Present case study including different signs and
symptoms, alternative treatment of asthma, pharmaceutical care plan and
discharge counselling etc.
Describe different types of drug interaction with suitable examples.