B.Pharm. (Semester III) (Old CBCS) Examination, 2018
PATHOPHYSIOLOGY AND CLINICAL BIOCHEMISTRY I
Day and Date Friday, 28-12-2018 Max. Marks 70
Time 2.30 p.m. to 5.30 p.m.
1. Multiple Choice Questions. (15×1=15)
Identification of disease is termed as
Diagnosis Prognosis
Dialysis Therapeutic drug monitoring
Which of the following is responsible for maintaining of calcium levels in
body
Aldosterone Anti-diuretic Hormone
Atrial Natriuretic Peptide Parathyroid Hormone
Reduction in blood flow to a particular part of the body is known as
Necrosis Ischemia
Infarction Hypoxia
Gall stone is also known as
Cholestasis Cholelithiasis
Cholecystitis Hepatoblastoma
Clinical manifestation of nephrotic syndrome includes
Heavy proteinuria Hypoalbuminaemia
Hyperlipidaemia All of the above
Pain-food-relief pattern is observed in case of
Enterocolitis Gastric ulcers
Duodenal ulcers Crohn's disease
Loss of appetite is known as
Insomnia Nausea
Anorexia Alopecia
Seat
No. Set P
Set P
SLR-TV 23 *SLRTV23*
Nuclear fragmentation into small bits dispersed in the cytoplasm is known
as
Pyknosis Karyolysis
Karyorrhexis Amorphous density
The sign of inflammation describing edema is
Rubor Calor Dolor Tumor
10) Which of the following type of cell in GIT is majorly responsible for secretion
of mucus
Chief cell Parietal cell
Goblet cell Peptic cells
11) Renal ischemia can be categorized under cause of acute renal
failure.
Pre-renal Renal
Post renal Extra renal
12) Growth promoting genes are called as
Proto-oncogenes Anti-oncogenes
Apoptosis regulatory genes DNA repair genes
13) change in reversible injury is also known as glassy change
Hyaline Fibrinoid Hydropic Fatty
14) Increase in the concentration of potassium is called as
Hypernatraemia Hypercalcaemia
Hyperkalaemia Hypovolaemia
15) The nerve fiber involved in the pathway for slow pain
Aδ- C K-fiber
2. Answer any five of the following questions.
Draw flowchart of Renin-Angiotensin-Aldosterone pathway.
Write a note on types of glomerulonephritis.
Set P
*SLRTV23* SLR-TV 23
Define inflammation. Describe the effects of altered vascular
permeability.
Give the types, causative organisms and symptoms of viral hepatitis.
Define Atrophy, Hypertropy, Hyperplasia, Metaplasia and Dysplasia.
Define neoplasia. Describe the risk factors for cancer.
3. Answer any three of the following questions. (3×10=30)
Write a note on pathogenesis and clinical complications of Chronic Renal
failure.
Describe the etiopathogenesis and clinical manifestations of peptic ulcer.
Define apoptosis. Explain in detail the mechanism of apoptosis.
Write a note on types, causes, symptoms and complications related to
cancer.