OCTOBER 2017 Sub. Code: 2907
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH II PHARMACEUTICAL CHEMISTRY
PAPER IV NATURAL PRODUCTS OF MEDICINAL INTEREST
Q.P. Code 262907
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. The structural elucidation of morphine.
2. Discuss the significance of natural products as leads for new pharmaceutics.
Discuss the chemistry of natural hormones derived from steroids.
II. Write notes on: (10 x 6 60)
1. The structural determination of Psoralene.
2. Structural features of streptomycin.
3. Macrolide antibiotics.
4. Application of HPLC to separation and analysis of plant constituent.
5. The significance of pharmaceutical products based on novel bio-technology.
6. The mechanism of action and chemistry of penicillins.
7. Carbapenems and penems.
8. Antisense oligonucleotide therapy.
9. The chemistry of quercetin.
10. Gymnema sylvestre.