Exam Details

Subject naturalproducts of medicinal interest
Paper paper 4
Exam / Course m.pharm.pharmaceutical chemistry
Department
Organization Dr.M.G.R. Medical University
Position
Exam Date May, 2017
City, State tamil nadu, chennai


Question Paper

MAY 2017 Sub. Code: 2907
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH II PHARMACEUTICAL CHEMISTRY
PAPER IV NATURAL PRODUCTS OF MEDICINAL INTEREST
Q.P. Code 262907
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. The application of the following analytical techniques in the isolation,
identification and analysis of plant constituents-GLC, HPLC, MS, ORD and CD.
2. The following methods of employed in structure elucidation of natural products.
Hoffmann's exhaustive methylation.
Herzig Meyer method.
Ziesel's method of determination of methoxy groups.
Zerewitinoff's method.
II. Write notes on: (10 x 6 60)
1. Steroid receptors.
2. Milbenmycins as lead for new pharmaceuticals.
3. Polypeptide antibiotics.
4. Lincomycins.
5. Mechanism of action of Nocardicins.
6. New biological targets for drug development.
7. Stereo chemistry of the steroid nucleus.
8. Mechanism of action of Beta lactamase inhibitors.
9. Acute constituents in pterocarpus marsupiam.
10. Constitution of streptomycin.



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Subjects

  • advanced medicinal chemistry
  • advanced organic chemistry
  • naturalproducts of medicinal interest