1. TheCommitlee appointed by Govemment ofIndia to look into the drug indu.stry and various aspects of drugs like licensing, price control, imports, role of foreign sector, quality control was headed by

Mudaliar

Bhatia

Hathi

Bhore

2. The PoisonActwas introduced in theyear

1878

1894

1919

1930

3. One of the following is not correct in the mainofobjectivesofPharmacyAct, 1948 of India

Restoration of pharmacy profession In its due place in the health service

Raising the status of pharmacy profession

To regulate the practice of pharmacy

To have common syllabus of -pharmacy thr.oughout India

4. Fine for false claim to be a registered pharmacist on first conviction is

RS.500 BQ-1A116

6 months imprisonment

Rs.1,000,

Both fine and imprisonment

5. The main objective of Drugs and Cosmetics Act, 1940 and subsequent amendments is to regulate the import, manufacture, distribution and sale of drugs and cosmetics of allopathy and the following categories except:

Ayurveda

Siddha

UnaniTibb

Homoeopathy

6. One of the following does not come under the purview of PCI

Education regulations

Recognition of foreign qualification

Approval of pharmacy institutions and withdrawal of approvals

Issuing licenses to.pharmacists

7. The sale of opium to the State Governments or manufacturing chemists is made by Central Government Opium Factory located at:

Ghaziabad

Ghazipur

Ghorakhpur

Goa

8. Pharmacy Council of India was constituted in which year?

1949

1948

1947

1950

9. All products of parenteral use are listed under the following Schedule:

A

B

C

D

10. The total number of State Pharmacy Council members are:

10

15

20

25

11. The first edition of Indian Pharmacopoeia wasout in

1945

1950

1955

1960

12. Applications for grant or renewal of license for manufacturing Ayurvedic, SQ -1A116 Siddha and Unani drug is required to be made in

Form 24-0

Form 48

Form 25-E

Form 24-E

13. Drugs to be taken under the medical supervision are included under the following Schedule:

E

G

H

K

14. The Drugs (Price Control) Order, 1995 does not take into account one of the following in fixing the retail price:

Material cost and conversion cost

Packing material and packing charges

Excise duty

Local taxes

15. New drugs developed through research are exempted from price control for a period of:

5years

10 years Contd.

15 years .

20 years

16. As. per the Shops and EstablishmentAct young persons (12-18 years) should not be made to work more than one of the following hours per day:

4 hours

6 hours

8 hours

10 hours

17. Forms used to send a memorandum to GovemmentAnalyst under ScheduleA is done in

Form 14-A

Form 18 and 18-A

Form 15

Form 19

18. License for retail of drugs specified in Schedule X is given in the following form

20-A

20-B

20-F

2D-G

19. The effectiveness of the new drug is confirmed in one ofthe following phases of clinical trials:

Phase I BQ-1N16

Phase II

Phase III

Phase IV

20. The list of diseases and ailments that a drug should not claim to cure are given in the following schedule of Pharmacy Act, 1940:

H

J

K

M

21. The Drugs and Magic Remedies Act came into force in

1953

1954

1955

1956

22. Ayurvedic preparations containing less than the following of self generated alcohol are exempted from excise duty as per the Medicinal and Toilet Preparations (Excise Duties) Act, 1955:









23. One of the following is not a member of theiAEC:

Biologist

Veterinarian

Social worker

Advocate

24. One of the following is not an essential commodity as per the Act 1955

Raw Jute

Cotton Textiles

Petroleum Products

Raw Wool

25. Under New Drug Policy, 1994, with National Drug Authority, the Central Government has the responsibility of granting license itself to the following except:

Large volume parenterals

Sera and vaccines

Whole human blood and blood products

Small volume parenterals

26. As per the Code of Pharmaceutical Ethics a registered pharmacist can not do the following except:

Dispense drugs on humanitarian grounds

Render first acid in emergencies

Prescribe remedies in emergencies

Can practice medicine in emer­gencies

27. AspertheShopsandEstablishmentAct pharmacies differ from others in one of the following:

Hours of work for employees

Cleanliness ventilation and lighting

Wages for employees

Opening and closing times

28. The first National Institute for Pharmacy Education and Research (NIPER) was started at:

Banaras

Chennai

Mohali

Chandigarh

29. Regarding functions of the Pharmacy Councils in India one of the following is not correct:

A State Council takes care of the corresponding State

A State Council can serve the need of another State

There can be Joint Council to serve the need ofboth the States

The Central Council can also serve

30. AsperlheMedicinalandToiletPreparations Act, "Bonded Laboratories" means:

Excise duty has not been paid

Excise duty has been paid

Excise duty need not be paid

None of the above

31. In one of the following alkaloids, the nitrogen atom is secondary amine:

Mescaline

Ephedrine

Atropine

d-tuboaurarine

32. Asiaticosides are present as active constituents in

Nuxvomica

Opium

Tulsi

Brahmi

33. Opium is the dried latex obtained by vertical incisions of the following part of papaver somniferum

Ripe capsules

Unripe capsules

Semiripe capsules

All of the above
34. The alkaloidal content in atropa bella­donna is highest in the following part

Root

Leaf

Berries

Seeds

35. The following species Rauwolfia is indigenous to West Indies:

R. Serpentina

R. Vomitoria

R. Nitida

R. Tetraphylla

36. The following are involved as precursors forthe biosynthesis ofcinchona alkaloids except:

Indole

Anthanilic acid

Tryptophan

Geraniol

37. The active constituents in senna and aloes are Anthracene:

Alkaloids

Glycosides

Polymers

Esters

38. Spanish foxglove is

Digitalis purpurea

Digitalis lanata

Digitalis lutea

Digitalis thapsi

39. The botanical name for Tulsi is

Thevelia nerifolia

Tinospora cordifolia

Triticum aestivum

Oscimum sanctum

40. The primary metabolites for alkaloid synthesis in plants are:

Carbohydrates

Amino acids

Proteins

Peptides

41. A lubricating cream should possess the following properties except:

It should spread easily

It should not have good skin absorption

It should not be sticky in nature

It should be smooth in nature with less oiliness

42. In limulus Amoebocyte Lysate Test the extract from the blood ceil of which crustacea is used

Octopus

Horse Shoe Crab

Lobsters

Elephant Shoe Crab

43. The first edition of Pharmacopoeia of India was published in

1936

1946

1955

1966

44. Hydrolytic Resistance Test is performed on glass in order to find out:

Mechanical strength

Quality

Limit of alkalinity liberated by it

Impermeability

45. The approximate capacity of the capsule numbe zero is
950 mg

450 mg

300 mg

100 mg

46. Schick Test is performed to test the degree of immunity of an individual against:

Syphilis

Tetanus

Tuberculosis

Diphtheria

47. How much quantity of 60% alcohol required to make one liter of 45% of alcohol?

2 liter

500 ml

300 ml

750 ml

48. Avoid cheese, chocolate and red meat in patient those who are under therapy:

Benzodiazepines

Phenothizines

MAO inhibitors

Prednisolone

49. Transdermal drug delivery system has the following advantages except:

Side effects are reduced

Patient compliance is improved

First pass metabolism is not avoided

Duration of action is increased

50. Drug which produce malignant hyper­thermia is:

Diazepam

Halothane

Chloroquine

Phenytoin

51. Hoffman elimination is seen in

d-Tubocurosine

Atrocurium

Hexamethonium

Ether

52. Aspirin is lipid soluble when the medium has:

LowpH

High pH

Both of the above

None of the above

53. Which drug generally obey zero order kinetics?

Alcohol

Ampicillin

Atenolol

Adrenalin

54. Which antihistamine is now withdrawn from market due to its cardic toxicity

Terfenadine

Fexofenadine

Cetrizine

Loratidine

55. Which bird is generally taken for the bio­assay of digitalis?

Parrot

Pigeon

Sparrow

Fowl

56. Which is not a brand name of amlodipine

NUMLO

ATCOM

AMTAS

STAMLO

57. Which is a non-BZD newer hypnotics

Zileuton

Zoledronate

Zolpidem

Zolmitriptan

58. For treatment ofMorphine dependence, the drug used is

Naloxone

Disulfiram

Methadone

Midazolam

59. Which is a potent mineralocorticoid?

Dexamethasone

Fludrocortisone

Prednisolone

Hydrocortisone

60. For Pyrogen Test which animal is taken for experiment?

Rat

Cat

Rabbit

Hamster

61. Which is a inhaled corticosteroids?

Hydrocortisone

Budesonide

Prednisolone

Dexamethasone

62. Which is not a brand name of Ibuprofen?

BRUFEN

SUGAFEN

TABALON

TORVIN

63. The minimum area requirement for store­room of a 700 beds hospital is

1000 sq. feet

1600 sq. feet

2400 sq. feet

3600 sq. feet

64. For drugs which are given as enteric coated tablet, all the following are true, except:

Drugs which are destroyed in the acidic medium of the stomach

Produce irritation in stomach

Absorption takes place in intestine

Early action of drug is required
65. Which vaccine is prepared from live bacteria?

Cholera Contd.

Typhoid

BCG

Pertussis

66. Which is a tri-cyclic antidepressant?

Fluoxetine

Paroxetine

Amoxapine

Sertaline

67. Which is the most potent opioid analgesic?

Pentazocin

MORPHINE

FENTANYL

Buprenorphine

68. Which one is the brand name of Nifedipine

Cardilox

Calcigard

Calaptin

Corvadil

69. Bioassay gives the idea about of the test drug.

Unit quantity of the drug

Efficacy of the drug

Safety of the drug

Chemical structure of the drug

70. According to I. P. Syrup has density at 20°C is:

1.213

1.113

1.313

1.413

71. Which is not true for evaluation of suspen­sions?

Determination of rate of sedimen­tation

Determination of viscosity

Determination of Zeta potential

Determination of pH and stabilising agent

72. For a good ophthalmic solution the dis­persed particle should be very fine in size:

Not greater than 5 micron

Not greater than 10 micron

Not greater than 15 micron

Not greater than 20 micron

73. Which one is a synthetic anionic emulsifying agent?

Benzalkonium

Sodium lauryl sulfate

Cetyl trimethyl ammonium bromide

Tragacanth

74. For preparation of a primary emulsion by peppermint oilthe Oil: water: Gum should be:

2



1

1 1

75. If an object or a solution absorbs blue light then the transmitted colour will be

Green

Yellow

Violet

BJue

76. All are essential components of colorimete except:

Photocell

Galvanometer

A light source

Thermometer

77. Nephlometer is used to determine:

Concentration of Nephron in Kidney

Number of Nephron in Kidney

Concentration of a dispersed phase of a suspension

Concentration of radiation of the substance

78. Which is a angiotensin receptor blocker?

Telmisartan

Terazocin

Ticlopidine

TimoloJ

79. Which phosphodiesterase inhibitor can be used in congestive heart failure?

Midazolam

Mitrinone

Mivacurium

Miltefosin

80. Which is a atypical antipsychotic drug?

Haloperidol

Olanzapine

Thioridazine

Penfluridol

81. Which is a anabolic steroid?

Stanozolol

Salmeterol

Satranidazol

Sotalol

82. Epoxide intermediates are formed during metabolism of which drug?

Alcohol

Paracetamol

Procaine

Clozapine

83. For bio-assay of Vit. B12, the micro­organism taken is

Lactobacilus leichmannii

Lactobacilus acidophilus

Lactobacilus plantarum

Lactobacilus rhamnosus

84. All drugs excretion is enhanced in alkaline urine except:

Salicylate

Pethidine

Barbiturate

Sulfadoxine

85. Reye's syndrome occurs in children if having viral infection, takes the drug:

Aspirin

Paracetamol

Ampicillin

Ibuprofen
86. Which of the following drug is not given by intravenous root?

Heparin

Nitroglycerine

Neomycin

Linezolide

87. Which one of the following drug can be safely given to G-6-PD deficient patient?

Vitamin K (water soluble derivatives)

Primaquine

Dapsone

Propranolol

88. What is true regarding the highly ionized drug?

Mainly excreted by the kidney

Accumulates in the cellular lipids

Highly protein bound

Should be given by oral route only

89. Which of the following is an example of physiological antagonism?

Protamine in case of heparin toxicity

Terbutaline in leukotrienes mediated bronchoconstriction

Reduction of anticoagulant effect of warfarin in presence of phenobar­bitone

Urinary alkalisers for poisoning due to salicylates

90. Microsomal enzymes induction can result:

Tolerance

Dependence

Super sensitivity to drug

Drug toxicity

91. Therapeutic drug monitoring is indicated in:

Insulin therapy

Anti hypertensive therapy

Lithium

Oral anticoagulant

92. In phase I clinical trial Mr. X was given new drug. The clearance and volume of 1 (Turnover) distribution in Mr. X is 1.296 Uhrand 75 L respectively. The half life of drug will be:

20 hr

40 hr

80 hr

120 hr

93. Which of the following drug shows therapeutic window phenomenon?

Diazepam

Insulin

Warfarin

Imipramine

94. A 8 days old new born is suffering from un conjugated hyperbilirubinaemia, the risk of kernicterus will be increased with the use of the following drug:

Sulphonamide

Phenobarbitone

Amoxycilline

Amikacin

95. Which of the following statement regarding loading dose is true?

Aim is to quickly achieve therapeutic concentration

It is done to individualiZe the therapy

It is-always single drug administra­tion

It is governed by clearance and plasma half life

96. Regarding the controlled release of dosage form of drug, which of the following statement is not true?

Bioavailability of some drug can be improved

It can improve patient's compliance

Drugs with short half lives are not suitable for making controlled release preparations

Dose dumping can lead to drug toxicity

97. Which of the following is not an example of targeted drug delivery system? .

Nano particles

Drug eluting stent

Pilocarpine ocusert

Transdermal system

98. Therapeutic index of drug is a indicator of:

Safety

Potency

EffICaCY

Potency and Efficacy
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