THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
(LO 2005) MARCH 2019 Sub. Code: 2005
B.PHARM. DEGREE EXAMINATION
PCI Regulation SEMESTER I
PAPER III PHARMACEUTICS I
Q.P. Code: 562005
Time: Three hours Maximum: 75 Marks
I. Elaborate on: Answer any TWO questions. x 10 20)
1. Discuss the various solubility enhancement techniques.
2. Write the mechanism of dermal penetration. Explain the method of preparation of
creams.
3. What are suspensions? Give classification of suspensions. Explain different
components used for preparation of suspension.
II. Write notes on: Answer any SEVEN questions. x 5 35)
1. Discuss history and development of profession of pharmacy in India.
2. Discuss different errors in prescription.
3. How will you prepare 200 ml of 60 percent alcohol from 90 percent and 50
percent alcohols.
Calculate the dose for a 9 years old child when the adult dose is 250mg.
4. Discuss the bulk powders which meant for external use.
5. Write a note on Elixir. Give the difference between Syrup and Elixir.
6. Discuss the Suspending agents used to stabilize the suspensions.
7. Write note on Instability of emulsions.
8. Explain how Suppositories are evaluated.
9. Give the fusion method preparation of ointment with a suitable example.
III. Short answers on: Answer ALL questions. (10 x 2 20)
1. What do you understand by Indian Pharmacopoeia?
2. Give advantages and disadvantages of liquid dosage form.
3. What is an inscription?
4. How pediatric dose is calculated on the basis of body weight?
5. Give the types of dusting powders.
6. What are Preservatives? Give an example.
7. What are Ear drops?
8. Give the qualities of a good suspension.
9. What are Emulsifying agents? Give examples.
10. Differentiate between ointments and pastes.