THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
(LO 2031) MARCH 2019 Sub. Code: 2031
B.PHARM. DEGREE EXAMINATION
PCI Regulation SEMESTER III
PAPER I PHARMACEUTICAL ORGANIC CHEMISTRY II
Q.P. Code: 562031
Time: Three hours Maximum: 75 Marks
I. Elaborate on: Answer any TWO questions. x 10 20)
1. Discuss three different methods of synthesis of Anthracene. Mention some of its
important properties. How can be Anthracene converted to anthraquinone and
alizarine.
2. Explain the preparation and effect of substituents on the acidic character of
phenols.
3. Define aromatic electrophlic substitution reactions. Discuss the reaction and
mechanism of Nitration, Halogenation, Sulphonation, Friedel-craft alkylation and
Friedel-craft arylation.
II. Write notes on: Answer any SEVEN questions. x 5 35)
1. Write any three methods for synthesis of Diphenyl methane.
2. Explain chemical reactions of aromatic carboxylic acids.
3. What are the methods used for the synthesis of phenanthrene.
4. Discuss the basicity of amines.
5. Write the preparation and synthetic utility of diazonium compounds.
6. Explain about Resonance theory of benzene.
7. Write any five reactions of naphthalene.
8. What are lipids? Write their classification in detail.
9. Write a note on Bayer's strain theory.
III. Short answers on: Answer ALL questions. (10 x 2 20)
1. Difference between an oil and fat.
2. Hinsberg test.
3. Structure and uses of DDT and BHC.
4. Waxes.
5. Hybridization.
6. Mechanism of Halogenation of benzene.
7. Fatty acids.
8. Sachse Mohr's theory.
9. Saponification value.
10. Structure and use of Cresol and Resorcinol.