THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
(LO 2003) MARCH 2019 Sub. Code: 2003
B.PHARM. DEGREE EXAMINATION
PCI Regulation SEMESTER I
PAPER II PHARMACEUTICAL ANALYSIS I
Q.P. Code: 562003
Time: Three hours Maximum: 75 Marks
I. Elaborate on: Answer any TWO questions. x 10 20)
1. Explain the principle and procedure involved in the assay of calcium gluconate.
2. What is a neutralization curve? Explain the titration curves of strong acid with
strong base and weak base.
3. Explain in detail the construction and working of silver silver chloride electrode.
II. Write notes on: Answer any SEVEN questions. x 5 35)
1. Explain the principle of sulphate limit test.
2. Preparation and standardization of 0.1M sodium hydroxide solution.
3. Note on Mohr's method.
4. Discuss the theory of redox titrations.
5. What is masking? Write its significance in analysis.
6. Explain the various types of currents of polarographic method.
7. Preparation and standardization of 0.1N sodium thiosulphate solution.
8. Explain the estimation of Barium sulphate by gravimetry.
9. Write the basic concept of conductometric titrations.
III. Short answers on: Answer ALL questions. (10 x 2 20)
1. Write about quantitative and qualitative analysis.
2. Explain the principle of back titration.
3. What is a primary standard? Mention one e.g. and its ideal property.
4. Define Amphiprotic solvents with e.g.
5. Write two application of polarography.
6. Nernst Equation.
7. Preparation of 0.1N Oxalic acid.
8. Write about personal errors.
9. Mention the indicator electrode used in Potentiometry.
10. Define Metal ion indicators with e.g.